Sugi Predict

Sugi Predict / Targets / DDX5

DDX5

Probable ATP-dependent RNA helicase DDX5 · P17844 · DDX5 on Sugi Atlas →

676 patent compounds predicted against DDX5, 571 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL9563404 SCHEMBL9563404 1.00 1/20
SCHEMBL18296600 SCHEMBL18296600 1.00 1/20
SCHEMBL20286453 SCHEMBL20286453 1.00 1/20
SCHEMBL29429769 SCHEMBL29429769 1.00 1/20
SCHEMBL29473358 SCHEMBL29473358 1.00 1/20
SCHEMBL30255916 SCHEMBL30255916 1.00 1/20
SCHEMBL13931437 SCHEMBL13931437 0.90 1/20
SCHEMBL18296599 SCHEMBL18296599 0.90 1/20
SCHEMBL25932530 SCHEMBL25932530 0.84 1/20
SCHEMBL3513607 SCHEMBL3513607 0.80 1/20
SCHEMBL6786007 SCHEMBL6786007 0.80 1/20
SCHEMBL15342071 SCHEMBL15342071 0.80 1/20
SCHEMBL27764694 SCHEMBL27764694 0.80 1/20
SCHEMBL16649085 SCHEMBL16649085 0.79 1/20
SCHEMBL3138027 SCHEMBL3138027 0.79 1/20
SCHEMBL24978781 SCHEMBL24978781 0.79 1/20
SCHEMBL15677142 SCHEMBL15677142 0.77 1/20
SCHEMBL3278215 SCHEMBL3278215 0.76 1/20
SCHEMBL6366782 SCHEMBL6366782 0.76 1/20
SCHEMBL18296780 SCHEMBL18296780 0.76 1/20

Clinical trials — most relevant to DDX5 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Reverse Transcriptase Inhibitors in AGS PHASE2COMPLETED
Treatment of Refractory Diamond-Blackfan Anemia With Eltrombopag PHASE1/PHASE2COMPLETED
Genomic Responses of Human Immune and Non-Immune Cells to Glucocorticoids PHASE1COMPLETED
Study of Individuals and Families With Aberrations in DDX41 or Similar Cancer Predisposition Variants nanRECRUITING
DDX3X Syndrome -The Seaver Autism Center for Research and Treatment is Characterizing DDX3X-related Neurodevelopmental Disorders Using Genetic, Medical, and Neuropsychological Measures. nanCOMPLETED
Better Delineation of DDX3X Related Phenotype and Epigenetic Signature. nanUNKNOWN
Gene Mutations and Rescue in Human Congenital Diaphragmatic Hernia nanUNKNOWN
Studying Chromosomes in Samples From Younger Patients With Neuroblastoma nanCOMPLETED
DICER1-related Pleuropulmonary Blastoma Cancer Predisposition Syndrome: A Natural History Study nanRECRUITING
Exome Analysis in Hearing Impaired Patients nanUNKNOWN
PCD New Gene Discovery nanCOMPLETED
Cause of Familial Testicular Cancer nanCOMPLETED
Molecular Basis of Pediatric Liver Cancer nanRECRUITING
Whole-genome Sequencing Study in Patients With Diminished Ovarian Reserve nanUNKNOWN
Diamond Blackfan Anemia Registry (DBAR) nanRECRUITING
Immunogenetics of Visceral Leishmaniasis nanCOMPLETED
Diaphragmatic Hernia Research & Exploration, Advancing Molecular Science nanRECRUITING
Genetic Analysis of Heart Channelopathies in Brazilian Patients and Their Relatives nanUNKNOWN
MiRNA223 and HMGB1 as Apredictos for Drug Resistant Epilepsy nanUNKNOWN
International PPB/DICER1 Registry nanRECRUITING
Differential Gene Expression of Liver Tissue and Blood From Individuals With Chronic Viral Hepatitis nanUNKNOWN
Clinical Manifestations and Biomarkers in Amyotrophic Lateral Sclerosis Type 4 and Other Inherited Neurological Disorders of RNA Processing nanRECRUITING
Pilot Study: Gene Expression Profiling of Immune Response to HBV Vaccination in Healthy Volunteers nanCOMPLETED
Study of Specimens From Young Patients With Neuroblastoma nanCOMPLETED
ADAR1 Expression Level in Rectal Cancer nanRECRUITING
Screening for Early Pancreatic Neoplasia (Cancer of the Pancreas Screening or CAPS4 Study) nanCOMPLETED
Chromosome 5Q Gene Variants and Asthma-Related Traits nanCOMPLETED
The Value of circRNAs (hsa_circ_0004001) in Early Diagnosis of HCC nanUNKNOWN
Study of the Sex Differences in Inflammatory Diseases in Children nanUNKNOWN
Studying Biomarkers in Samples From Younger Patients With Wilms Tumor nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a DDX5 binder may also engage these)

ProteinNameSimilarity
A5A6J2 — 1.000 A5A6J2 →
Q61656 — 1.000 Q61656 →
Q4R6M5 — 1.000 Q4R6M5 →
Q5R4I9 — 1.000 Q5R4I9 →
P24782 — 1.000 P24782 →
Q501J6 — 1.000 Q501J6 →
A1C6C4 — 0.999 A1C6C4 →
Q8W4R3 — 0.999 Q8W4R3 →
Q6CIV2 — 0.999 Q6CIV2 →
Q6FLF3 — 0.999 Q6FLF3 →
Q26696 — 0.999 Q26696 →
A3LQW7 — 0.998 A3LQW7 →
Q4X195 — 0.997 Q4X195 →
Q2U070 — 0.996 Q2U070 →
Q62167 — 0.996 Q62167 →
Q4P733 — 0.996 Q4P733 →
O13370 — 0.996 O13370 →
Q62095 — 0.996 Q62095 →
Q8TFK8 — 0.996 Q8TFK8 →
A6R3L3 — 0.995 A6R3L3 →
P24783 — 0.995 P24783 →
Q75HJ0 — 0.995 Q75HJ0 →
A4QSS5 — 0.995 A4QSS5 →
A1DGZ7 — 0.995 A1DGZ7 →
A2QC74 — 0.994 A2QC74 →
Q6FP38 — 0.994 Q6FP38 →
Q61496 — 0.994 Q61496 →
Q75B50 — 0.994 Q75B50 →
Q9LYJ9 — 0.994 Q9LYJ9 →
P0CQ74 — 0.994 P0CQ74 →