⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28261945 | 0.84 | LMNA (0.40) | — | |
| SCHEMBL11839869 | 0.76 | — | — | |
| SCHEMBL15699653 | 0.75 | — | — | |
| SCHEMBL10315016 | 0.75 | — | — | |
| SCHEMBL14026590 | 0.74 | TDP1 (0.39) | — | |
| SCHEMBL9375070 | 0.74 | TSHR (0.39) | — | |
| SCHEMBL9871855 | 0.74 | GAA (0.48) | — | |
| SCHEMBL9754935 | 0.74 | TSHR (0.41) | — | |
| SCHEMBL15820454 | 0.74 | PIK3CD (0.33) | — | |
| SCHEMBL28152294 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100022467-A1 | ANTI-CANCER PHOSPHONATE ANALOGS | BOOJAMRA CONSTANTINE G | 2010-01-28 | — | — | US | disclosed |
| US-20090275535-A1 | ANTIVIRAL PHOSPHONATE ANALOGS | GILEAD SCIENCES, INC. | 2009-11-05 | — | — | US | disclosed |
| US-7452901-B2 | Anti-cancer phosphonate analogs | GILEAD SCIENCES, INC. (US) | 2008-11-18 | — | — | US | disclosed |
| US-7429565-B2 | Antiviral phosphonate analogs | GILEAD SCIENCES, INC. (US) | 2008-09-30 | — | — | US | disclosed |