Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.43 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10074092 | 0.87 | MEN1 (0.58) | MEN1KMT2ANPSR1HDAC1TSHR | |
| SCHEMBL10073212 | 0.82 | CYP1A2 (0.49) | MEN1KMT2ANPSR1HDAC1CYP1A2 | |
| SCHEMBL13534535 | 0.81 | HRH3 (0.51) | MEN1KMT2ANPSR1HDAC1TSHR | |
| SCHEMBL10074089 | 0.81 | CYP1A2 (0.46) | HDAC1CYP1A2HSD17B10 | |
| SCHEMBL13533056 | 0.80 | TP53 (0.53) | HDAC1 | |
| SCHEMBL30454657 | 0.77 | PTGDR2 (0.44) | HDAC1PARP1HSD17B10 | |
| SCHEMBL22391864 | 0.77 | PTGDR2 (0.44) | HDAC1PARP1HSD17B10 | |
| SCHEMBL14095609 | 0.75 | KMT2A (0.97) | MEN1KMT2ANPSR1TSHRALDH1A1 | |
| SCHEMBL1337663 | 0.75 | KMT2A (0.97) | MEN1KMT2ANPSR1TSHRALDH1A1 | |
| SCHEMBL2708171 | 0.75 | MEN1 (0.55) | MEN1KMT2ANPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8071590-B2 | 9-substituted-5-carboxy-oxadiazino-quinolone derivatives, their preparation and their application as anti-bacterials | VETOQUINOL SA (FR) | 2011-12-06 | — | — | US | disclosed |
| US-8071590-B2 | 9-substituted-5-carboxy-oxadiazino-quinolone derivatives, their preparation and their application as anti-bacterials | VETOQUINOL SA (FR) | 2011-12-06 | — | — | US | disclosed |
| EP-2145891-A1 | 9-substituted-5-carboxy-oxadiazino-quinolone derivatives, their preparation and their application as anti-bacterials | VETOQUINOL S.A. (FR) | 2010-01-20 | — | — | EP | disclosed |
| WO-2010004394-A1 | 9-SUBSTITUTED-B-CARBOXY-OXADIAZINO-QUINOLONE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION AS ANTI-BACTERIALS | VETOQUINOL SA (FR) | 2010-01-14 | — | — | WO | disclosed |