Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR1E | P28566 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22391864 | 1.00 | PTGDR2 (0.44) | PTGDR2HDAC1GRM5DPP4HTR1A | |
| SCHEMBL29016272 | 0.79 | HDAC1 (0.41) | PTGDR2HDAC1GRM5DPP4HTR1A | |
| SCHEMBL22391775 | 0.77 | HTR2C (0.52) | DPP4HTR2AHTR2CHTR2B | |
| SCHEMBL30454467 | 0.77 | HTR2C (0.52) | DPP4HTR2AHTR2CHTR2B | |
| SCHEMBL10073212 | 0.77 | CYP1A2 (0.49) | HDAC1HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL13534595 | 0.77 | MEN1 (0.57) | HDAC1HSD17B10PARP1 | |
| SCHEMBL13534535 | 0.75 | HRH3 (0.51) | HDAC1HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL10074089 | 0.75 | CYP1A2 (0.46) | HDAC1HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL13533056 | 0.74 | TP53 (0.53) | HDAC1MAPT | |
| SCHEMBL22391942 | 0.73 | CACNA1G (0.51) | PTGDR2HTR1ADRD1HTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113227068-B | GLP-1R agonists and uses thereof | 上海齐鲁锐格医药研发有限公司 | 2023-06-13 | — | — | CN | disclosed |