Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | GPR183 | P32249 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13534655 | 0.99 | GPR119 (0.51) | GPR119KCNH2GPR183NPC1RAB9A | |
| SCHEMBL2390335 | 0.93 | GPR119 (0.48) | GPR119KCNH2GPR183NPC1RAB9A | |
| SCHEMBL2388880 | 0.92 | GPR119 (0.47) | GPR119KCNH2GPR183KMT2A | |
| SCHEMBL2387935 | 0.92 | GPR119 (0.47) | GPR119KCNH2GPR183KMT2A | |
| SCHEMBL2387931 | 0.92 | GPR119 (0.47) | GPR119KCNH2GPR183KMT2A | |
| SCHEMBL13534644 | 0.91 | GPR119 (0.58) | GPR119KCNH2GPR183HRH3 | |
| SCHEMBL1922600 | 0.90 | GPR119 (0.52) | GPR119KCNH2GPR183 | |
| SCHEMBL2388962 | 0.90 | GPR119 (0.46) | GPR119KCNH2GPR183NPC1RAB9A | |
| SCHEMBL2388969 | 0.90 | GPR119 (0.46) | GPR119KCNH2GPR183NPC1RAB9A | |
| SCHEMBL2399814 | 0.89 | GPR119 (0.51) | GPR119KCNH2GPR183 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010004347-A1 | HETEROCYCLIC GPCR AGONISTS | PROSIDION LIMITED (GB) | 2010-01-14 | — | — | WO | disclosed |