Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | GPR183 | P32249 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2387931 | 1.00 | GPR119 (0.47) | GPR119KCNH2GPR183ALDH1A1KDM4E | |
| SCHEMBL2388880 | 1.00 | GPR119 (0.47) | GPR119KCNH2GPR183ALDH1A1KDM4E | |
| SCHEMBL2388969 | 0.95 | GPR119 (0.46) | GPR119KCNH2GPR183 | |
| SCHEMBL2388962 | 0.95 | GPR119 (0.46) | GPR119KCNH2GPR183 | |
| SCHEMBL2389426 | 0.92 | GPR119 (0.53) | GPR119KCNH2GPR183ALDH1A1PDE2A | |
| SCHEMBL1923024 | 0.92 | GPR119 (0.53) | GPR119KCNH2GPR183ALDH1A1PDE2A | |
| SCHEMBL1923020 | 0.92 | GPR119 (0.53) | GPR119KCNH2GPR183ALDH1A1PDE2A | |
| SCHEMBL13534656 | 0.92 | GPR119 (0.51) | GPR119KCNH2GPR183KMT2A | |
| SCHEMBL2390335 | 0.91 | GPR119 (0.48) | GPR119KCNH2GPR183 | |
| SCHEMBL13534655 | 0.91 | GPR119 (0.51) | GPR119KCNH2GPR183 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110212939-A1 | Heterocyclic GPCR Agonists | PROSIDION LIMITED (GB) | 2011-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110212939-A1 | Heterocyclic GPCR Agonists | GPR119, GCGR, GPR27 | GPR119 1/4885KCNH2 1299/4885GPR183 29/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.