SCHEMBL135356

SCHEMBL135356

COC(=O)CCC(=O)c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A2 P43354 1/20 0.61
ESRRB O95718 1/20 0.57
MAPT P10636 5/20 0.56
KMT2A Q03164 5/20 0.56
TDP1 Q9NUW8 2/20 0.56
MEN1 O00255 2/20 0.56
HPGD P15428 2/20 0.56
KDM4E B2RXH2 2/20 0.56
MAPK1 P28482 2/20 0.56
AKT1 P31749 1/20 0.56
CYP3A4 P08684 1/20 0.56
ALOX15 P16050 1/20 0.56
CES1 P23141 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
LMNA P02545 4/20 0.55
L3MBTL1 Q9Y468 3/20 0.55
ALDH1A1 P00352 5/20 0.55
GAA P10253 1/20 0.55
CYP2C19 P33261 1/20 0.55
TSHR P16473 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene SCHEMBL8322482 0.96 NR4A2 (0.57) NR4A2ESRRBMAPTKMT2ATDP1
SCHEMBL10001233 0.89 SMN1; SMN2 (0.66) ESRRBMAPTKMT2AMEN1HPGD
SCHEMBL941120 0.89 TDP1 (0.62) NR4A2MAPTKMT2ATDP1MEN1
SCHEMBL6336402 0.89 TDP1 (0.68) NR4A2ESRRBMAPTKMT2ATDP1
SCHEMBL29048469 0.87 TDP1 (0.71) MAPTKMT2ATDP1MEN1HPGD
SCHEMBL6913209 0.87 TDP1 (0.71) MAPTKMT2ATDP1MEN1HPGD
SCHEMBL6156819 0.87 TDP1 (0.71) MAPTKMT2ATDP1MEN1HPGD
SCHEMBL4172632 0.87 TDP1 (0.71) MAPTKMT2ATDP1MEN1HPGD
SCHEMBL6205636 0.83 NR4A2 (0.65) NR4A2MAPTKMT2ATDP1MEN1
SCHEMBL275775 0.83 KMT2A (0.67) MAPTKMT2ATDP1MEN1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 230 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4532660-A1 DETERGENTS AND CLEANING AGENTS WITH AN IMPROVED ENZYME STABILITY Henkel AG & Co. KGaA (DE) 2025-04-09 EP claimed
EP-4532666-A1 DETERGENTS AND CLEANING AGENTS WITH AN IMPROVED ENZYME STABILITY Henkel AG & Co. KGaA (DE) 2025-04-09 EP claimed
WO-2023232193-A1 DETERGENTS AND CLEANING AGENTS WITH AN IMPROVED ENZYME STABILITY HENKEL AG & CO. KGAA (DE) 2023-12-07 WO claimed
WO-2023232194-A1 DETERGENTS AND CLEANING AGENTS WITH AN IMPROVED ENZYME STABILITY HENKEL AG & CO. KGAA (DE) 2023-12-07 WO claimed
WO-2026107406-A1 p53 HETEROBIFUNCTIONAL CONJUGATES AND USES THEREOF Design Therapeutics, Inc. (US) 2026-05-21 WO disclosed
US-12630554-B2 Pyrimidinone compounds and uses thereof HUTCHISON MEDIPHARMA LIMITED (CN) 2026-05-19 US disclosed
EP-4335914-B1 TEXTILE WASHING METHOD HENKEL AG & CO KGAA (DE) 2026-04-01 EP disclosed
EP-4705447-A1 PERFORMANCE-ENHANCED PROTEASE VARIANTS Henkel AG & Co. KGaA (DE) 2026-03-11 EP disclosed
US-20260043015-A1 PERFORMANCE-ENHANCED PROTEASE VARIANTS X HENKEL AG & CO KGAA (DE) 2026-02-12 US disclosed
EP-4618755-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2025-09-24 EP disclosed
EP-4573194-A1 PERFORMANCE-ENHANCED PROTEASE VARIANTS IX Henkel AG & Co. KGaA (DE) 2025-06-25 EP disclosed
EP-4573195-A1 PERFORMANCE-ENHANCED PROTEASE VARIANTS X Henkel AG & Co. KGaA (DE) 2025-06-25 EP disclosed
EP-0206741-B1 LEUKOTRIENE ANTAGONISTS MERCK FROSST CANADA INC. (CA) 1991-04-10 EP disclosed
US-4923891-A DIOXOLANE, DITHIOLANE AND OXATHIOLANE CARBOXYLATES, ANTIALLERGENS, ANTIINFLAMMATORIES G. D. SEARLE & CO. (US) 1990-05-08 US disclosed
US-4863904-A Dipeptides as renin inhibitors KISSEI PHARMACEUTICAL CO., LTD. (JP) 1989-09-05 US disclosed
EP-0308956-A2 Leukotriene LTD4 and LTB4 antagonists G.D. Searle & Co. (US) 1989-03-29 EP disclosed
US-4808729-A ANTIALLERGENS, ANTIINFLAMMATORY AGENTS G. D. SEARLE & CO. (US) 1989-02-28 US disclosed
EP-0181110-A2 Histidine derivatives as renin inhibitors Kissei Pharmaceutical Co. Ltd. (JP) 1986-05-14 EP disclosed
US-4325962-A ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIDYRETICS BYK-GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1982-04-20 US disclosed
US-4146721-A ANALGESICS, ANTIINFLAMMATORY AGENTS AND ANTIPYRETICS BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1979-03-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260043015-A1 PERFORMANCE-ENHANCED PROTEASE VARIANTS X CTRL, PRSS1, XPNPEP1 NR4A2 4740/4885ESRRB 2860/4885MAPT 3815/4885
US-12630554-B2 Pyrimidinone compounds and uses thereof CYP2D6, TPMT, CYP2B6 NR4A2 1196/4885ESRRB 2794/4885MAPT 1230/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.