Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.66 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 1/20 | 0.66 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 7/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.54 |
| ▸ | FEN1 | P39748 | 1/20 | 0.54 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | GSK3B | P49841 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10986985 | 0.90 | HDAC1 (0.63) | SMN1; SMN2LMNAFFAR1CYP1A2RAB9A | |
| SCHEMBL135356 | 0.89 | NR4A2 (0.61) | SMN1; SMN2LMNAHPGDL3MBTL1MAPT | |
| SCHEMBL7865396 | 0.86 | KMT2A (0.58) | SMN1; SMN2LMNAFFAR1CYP1A2RAB9A | |
| Ethylene SCHEMBL8322482 | 0.86 | NR4A2 (0.57) | SMN1; SMN2LMNAHPGDL3MBTL1MAPT | |
| SCHEMBL3821582 | 0.86 | ERCC5 (0.62) | SMN1; SMN2LMNAFFAR1CYP1A2RAB9A | |
| SCHEMBL11764964 | 0.85 | LMNA (0.56) | SMN1; SMN2LMNAFFAR1CYP1A2RAB9A | |
| SCHEMBL7925389 | 0.85 | KMT2A (0.59) | SMN1; SMN2LMNAFFAR1CYP1A2RAB9A | |
| SCHEMBL7924653 | 0.84 | SMN1; SMN2 (0.46) | SMN1; SMN2LMNAFFAR1CYP1A2RAB9A | |
| SCHEMBL7752972 | 0.83 | SMN1; SMN2 (0.65) | SMN1; SMN2LMNAFFAR1CYP1A2RAB9A | |
| SCHEMBL8534233 | 0.83 | SMN1; SMN2 (0.84) | SMN1; SMN2LMNAFFAR1CYP1A2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119504427-A | Preparation method of impurity I of fenbufen bulk drug | 华中药业股份有限公司 | 2025-02-25 | — | — | CN | disclosed |
| CN-119241326-A | Method for preparing deuterated aromatic hydrocarbon by catalyzing arylthianthrene salt through visible light | 郑州大学 | 2025-01-03 | — | — | CN | disclosed |
| CN-116623198-A | Method for preparing aromatic carbonyl compound by electrochemical oxidation reaction and aromatic carbonyl compound | 南开大学 | 2023-08-22 | — | — | CN | disclosed |
| US-8093427-B2 | Construction and screening of solution-phase derived library of fenbufen and ethacrynic acid | NATIONAL TSING HUA UNIVERSITY (TW) | 2012-01-10 | — | — | US | disclosed |
| US-8093427-B2 | Construction and screening of solution-phase derived library of fenbufen and ethacrynic acid | NATIONAL TSING HUA UNIVERSITY (TW) | 2012-01-10 | — | — | US | disclosed |
| US-20110306668-A1 | CONSTRUCTION AND SCREENING OF SOLUTION-PHASE DERIVED LIBRARY OF FENBUFEN AND ETHACRYNIC ACID | NATIONAL TSING HUA UNIVERSITY (TW) | 2011-12-15 | — | — | US | disclosed |
| US-20110306668-A1 | CONSTRUCTION AND SCREENING OF SOLUTION-PHASE DERIVED LIBRARY OF FENBUFEN AND ETHACRYNIC ACID | NATIONAL TSING HUA UNIVERSITY (TW) | 2011-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110306668-A1 | CONSTRUCTION AND SCREENING OF SOLUTION-PHASE DERIVED LIBRARY OF FENBUFEN AND ETHACRYNIC ACID | CYP4F2, ACR, CYP4F3 | SMN1; SMN2 2503/4885LMNA 1898/4885FFAR1 1407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.