SCHEMBL6205636

SCHEMBL6205636

O=C(CCC(=O)c1ccccc1)OC(=O)CCC(=O)c1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A2 P43354 1/20 0.65
MAPT P10636 4/20 0.59
L3MBTL1 Q9Y468 3/20 0.59
LMNA P02545 3/20 0.59
TDP1 Q9NUW8 3/20 0.59
ALDH1A1 P00352 4/20 0.59
GAA P10253 1/20 0.59
CYP2C19 P33261 1/20 0.59
KMT2A Q03164 3/20 0.57
MEN1 O00255 2/20 0.57
HPGD P15428 2/20 0.57
PRSS1 P07477 1/20 0.56
CTSG P08311 1/20 0.56
CTRB1 P17538 1/20 0.56
CMA1 P23946 1/20 0.56
MAPK1 P28482 3/20 0.55
USP2 O75604 1/20 0.55
POLB P06746 1/20 0.55
HTT P42858 1/20 0.55
NPSR1 Q6W5P4 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6205642 0.92 NR4A2 (0.57) NR4A2MAPTL3MBTL1LMNATDP1
SCHEMBL4826769 0.91 NR4A2 (0.55) NR4A2MAPTL3MBTL1LMNATDP1
SCHEMBL719034 0.86 NR4A2 (0.85) NR4A2MAPTL3MBTL1LMNATDP1
SCHEMBL30121738 0.86 NR4A2 (0.85) NR4A2MAPTL3MBTL1LMNATDP1
SCHEMBL8376781 0.85 NR4A2 (0.63) NR4A2MAPTL3MBTL1LMNATDP1
SCHEMBL27331403 0.83 NR4A2 (0.61) NR4A2MAPTL3MBTL1LMNATDP1
SCHEMBL135356 0.83 NR4A2 (0.61) NR4A2MAPTL3MBTL1LMNATDP1
SCHEMBL17992028 0.83 NR4A2 (0.61) NR4A2MAPTL3MBTL1LMNATDP1
SCHEMBL27964294 0.83 NR4A2 (0.61) NR4A2MAPTL3MBTL1LMNATDP1
SCHEMBL15485653 0.83 LMNA (0.54) NR4A2MAPTL3MBTL1LMNATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1317466-B1 SYNTHONS FOR OLIGONUCLEOTIDE SYNTHESIS AVECIA BIOTECHNOLOGY INC (US) 2005-02-23 EP disclosed
US-20030229218-A1 Synthons for oligonucleotide synthesis AVECIA BIOTECHNOLOGY INC. 2003-12-11 US disclosed
EP-1317466-A2 SYNTHONS FOR OLIGONUCLEOTIDE SYNTHESIS Avecia Biotechnology, Inc. (US) 2003-06-11 EP disclosed
WO-2002020543-A2 SYNTHONS FOR OLIGONUCLEOTIDE SYNTHESIS AVECIA BIOTECHNOLOGY INC. (US) 2002-03-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030229218-A1 Synthons for oligonucleotide synthesis POLI, TYMP, POLRMT NR4A2 4402/4885MAPT 3167/4885L3MBTL1 2317/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.