Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 2/20 | 0.59 |
| ▸ | PLD1 | Q13393 | 2/20 | 0.51 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.50 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.45 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | NCF1 | P14598 | 1/20 | 0.43 |
| ▸ | NMT1 | P30419 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31061236 | 1.00 | ADRB1 (0.59) | ADRB1PLD1PRKD1PRKD2HRH3 | |
| SCHEMBL13428642 | 0.87 | ADRB1 (0.55) | ADRB1PLD1HRH3DYRK1AHRH4 | |
| Hydrochloric Acid SCHEMBL31061321 | 0.86 | ADRB1 (0.54) | ADRB1PLD1HRH3DYRK1AHRH4 | |
| SCHEMBL18574083 | 0.84 | ADRB1 (0.52) | ADRB1PLD1PRKD1PRKD2HRH3 | |
| SCHEMBL8251254 | 0.84 | ADRB1 (0.52) | ADRB1PLD1PRKD1PRKD2HRH3 | |
| SCHEMBL18500387 | 0.80 | ADRB1 (0.51) | ADRB1PLD1HRH3DYRK1AHRH4 | |
| SCHEMBL30567171 | 0.78 | ADRB1 (0.64) | ADRB1PLD1PRKD1PRKD2HRH3 | |
| SCHEMBL22581914 | 0.78 | ADRB1 (0.64) | ADRB1PLD1PRKD1PRKD2HRH3 | |
| SCHEMBL21473853 | 0.78 | ADRB1 (0.49) | ADRB1PLD1HRH3DYRK1AHRH4 | |
| SCHEMBL24067234 | 0.78 | ADRB1 (0.46) | ADRB1PLD1HRH3DYRK1AHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2140864-A2 | Use of GAL3 receptor antagonists for the treatment of depression and / or anxiety and compounds useful in such methods | H.Lundbeck A/S (DK) | 2010-01-06 | — | — | EP | disclosed |