Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.45 |
| ▸ | NMT1 | P30419 | 7/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | AXL | P30530 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.39 |
| ▸ | MERTK | Q12866 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21475674 | 0.95 | ADRB1 (0.47) | ADRB1PLD1NMT1HRH4DYRK1A | |
| SCHEMBL18500387 | 0.89 | ADRB1 (0.51) | ADRB1PLD1NMT1HRH4DYRK1A | |
| SCHEMBL24067234 | 0.83 | ADRB1 (0.46) | ADRB1PLD1NMT1HRH4DYRK1A | |
| SCHEMBL13428642 | 0.81 | ADRB1 (0.55) | ADRB1PLD1NMT1HRH4DYRK1A | |
| Hydrochloric Acid SCHEMBL31061321 | 0.80 | ADRB1 (0.54) | ADRB1PLD1NMT1HRH4DYRK1A | |
| SCHEMBL8251254 | 0.78 | ADRB1 (0.52) | ADRB1PLD1NMT1HRH4DYRK1A | |
| SCHEMBL18574083 | 0.78 | ADRB1 (0.52) | ADRB1PLD1NMT1HRH4DYRK1A | |
| SCHEMBL13536716 | 0.78 | ADRB1 (0.59) | ADRB1PLD1NMT1HRH4DYRK1A | |
| SCHEMBL31061236 | 0.78 | ADRB1 (0.59) | ADRB1PLD1NMT1HRH4DYRK1A | |
| SCHEMBL23630383 | 0.76 | PIK3CA (0.48) | ADRB1PLD1NMT1AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10913730-B2 | Heteroaryl compounds and their use as Mer inhibitors | DONG-A SOCIO HOLDINGS CO., LTD. (KR) | 2021-02-09 | — | — | US | disclosed |
| US-20190315716-A1 | HETEROARYL COMPOUNDS AND THEIR USE AS MER INHIBITORS | DONG-A ST CO., LTD. (KR) | 2019-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10913730-B2 | Heteroaryl compounds and their use as Mer inhibitors | MERTK, RET, ERBB4 | ADRB1 198/4885PLD1 3285/4885NMT1 2614/4885 |
| US-20190315716-A1 | HETEROARYL COMPOUNDS AND THEIR USE AS MER INHIBITORS | MERTK, RET, ERBB4 | ADRB1 198/4885PLD1 3285/4885NMT1 2614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.