Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | CYP2A6 | P11509 | 5/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL885907 | 0.83 | L3MBTL1 (0.59) | L3MBTL1MAPK1NAMPTPDK2PRMT5 | |
| SCHEMBL12369720 | 0.82 | L3MBTL1 (0.65) | L3MBTL1CYP2A6CYP3A4ALDH1A1CYP1A2 | |
| SCHEMBL12395304 | 0.79 | L3MBTL1 (0.61) | L3MBTL1CYP2A6CYP3A4ALDH1A1CYP1A2 | |
| SCHEMBL12269974 | 0.78 | PRMT5 (0.45) | MAPK1NAMPTPDK2PRMT5WDR77 | |
| SCHEMBL19825676 | 0.78 | L3MBTL1 (0.63) | L3MBTL1CYP2A6CYP3A4ALDH1A1CYP1A2 | |
| SCHEMBL13036040 | 0.77 | PRMT5 (0.47) | L3MBTL1NAMPTPDK2PRMT5WDR77 | |
| SCHEMBL13827603 | 0.77 | L3MBTL1 (0.58) | L3MBTL1CYP2A6CYP3A4ALDH1A1CYP1A2 | |
| SCHEMBL13819903 | 0.76 | L3MBTL1 (0.57) | L3MBTL1CYP2A6CYP3A4ALDH1A1CYP1A2 | |
| SCHEMBL21054318 | 0.76 | NAMPT (0.41) | L3MBTL1MAPK1NAMPTPDK2PRMT5 | |
| SCHEMBL18625816 | 0.76 | KDR (0.54) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010010288-A2 | ALKYLTHIAZOL CARBAMATE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2010-01-28 | — | — | WO | disclosed |