Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | NAMPT | P43490 | 2/20 | 0.52 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.49 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.46 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17795050 | 0.84 | NAMPT (0.48) | L3MBTL1NAMPTPDK2PRMT5WDR77 | |
| SCHEMBL13537101 | 0.83 | L3MBTL1 (0.60) | L3MBTL1NAMPTPDK2PRMT5WDR77 | |
| SCHEMBL17864527 | 0.83 | NAMPT (0.47) | L3MBTL1NAMPTPDK2PRMT5WDR77 | |
| SCHEMBL15376325 | 0.83 | PRMT5 (0.50) | L3MBTL1NAMPTPDK2PRMT5WDR77 | |
| SCHEMBL13036040 | 0.82 | PRMT5 (0.47) | L3MBTL1NAMPTPDK2PRMT5WDR77 | |
| SCHEMBL15340952 | 0.81 | PRMT5 (0.49) | L3MBTL1NAMPTPDK2PRMT5WDR77 | |
| SCHEMBL21054318 | 0.81 | NAMPT (0.41) | L3MBTL1NAMPTPDK2PRMT5WDR77 | |
| SCHEMBL17806561 | 0.80 | ACHE (0.46) | L3MBTL1NAMPTPDK2PRMT5WDR77 | |
| SCHEMBL10094623 | 0.80 | PDK2 (0.54) | L3MBTL1NAMPTPDK2PRMT5WDR77 | |
| SCHEMBL11825580 | 0.80 | L3MBTL1 (0.53) | L3MBTL1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2429993-B1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | BOEHRINGER INGELHEIM INT (DE) | 2015-01-21 | — | — | EP | disclosed |