Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13537259 | 0.90 | MEN1 (0.38) | MEN1MAPTKMT2AHSD17B10ALDH1A1 | |
| SCHEMBL13537262 | 0.83 | MEN1 (0.39) | MEN1MAPTKMT2AHSD17B10ALDH1A1 | |
| SCHEMBL3358454 | 0.82 | ALDH1A1 (0.44) | MEN1MAPTKMT2AHSD17B10ALDH1A1 | |
| SCHEMBL13537363 | 0.82 | MEN1 (0.38) | MEN1MAPTKMT2AHSD17B10ALDH1A1 | |
| SCHEMBL13537632 | 0.81 | ALDH1A1 (0.37) | MEN1MAPTKMT2AHSD17B10ALDH1A1 | |
| SCHEMBL13537263 | 0.80 | MAPT (0.36) | MEN1MAPTKMT2AHSD17B10ALDH1A1 | |
| SCHEMBL13537540 | 0.75 | KMT2A (0.43) | MEN1MAPTKMT2AHSD17B10ALDH1A1 | |
| SCHEMBL13537424 | 0.75 | MEN1 (0.36) | MEN1MAPTKMT2AHSD17B10ALDH1A1 | |
| SCHEMBL13488665 | 0.72 | MEN1 (0.46) | MEN1MAPTKMT2AHSD17B10ALDH1A1 | |
| SCHEMBL3354225 | 0.72 | MEN1 (0.46) | MEN1MAPTKMT2AHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |