Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 19/20 | 0.77 |
| ▸ | HCAR3 | P49019 | 12/20 | 0.77 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acifran SCHEMBL188221 | 0.87 | HCAR2 (1.00) | HCAR2HCAR3CYP1A2 | |
| Acifran SCHEMBL5055334 | 0.87 | HCAR2 (1.00) | HCAR2HCAR3CYP1A2 | |
| SCHEMBL11293467 | 0.81 | HCAR2 (0.72) | HCAR2HCAR3CYP1A2 | |
| Acifran SCHEMBL11406401 | 0.80 | HCAR2 (0.78) | HCAR2HCAR3CYP1A2 | |
| Acifran SCHEMBL1876828 | 0.79 | HCAR2 (0.83) | HCAR2HCAR3CYP1A2 | |
| SCHEMBL11299766 | 0.78 | HCAR2 (0.67) | HCAR2HCAR3CYP1A2 | |
| SCHEMBL1585184 | 0.78 | HCAR2 (0.62) | HCAR2HCAR3CYP1A2 | |
| SCHEMBL1584901 | 0.76 | HCAR2 (0.63) | HCAR2HCAR3CYP1A2 | |
| SCHEMBL11301976 | 0.76 | HCAR2 (0.63) | HCAR2HCAR3CYP1A2 | |
| SCHEMBL3108561 | 0.75 | HCAR2 (0.76) | HCAR2HCAR3CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107243078-A | Make proprotein convertases subtilisin/types of KEXIN 9（PCSK9）The method of reduction | 克塔巴西斯制药有限公司 | 2017-10-13 | — | — | CN | disclosed |
| WO-2010009210-A2 | ACETYLSALICYCLIC ACID DERIVATIVES USEFUL TO TREAT METABOLIC SYNDROMES | SCHERING CORPORATION (US) | 2010-01-21 | — | — | WO | disclosed |