Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM2 | Q9P1W9 | 14/20 | 0.50 |
| ▸ | PIM1 | P11309 | 12/20 | 0.50 |
| ▸ | PIM3 | Q86V86 | 11/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | STK17B | O94768 | 2/20 | 0.41 |
| ▸ | BCL2 | P10415 | 2/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.41 |
| ▸ | CDK7 | P50613 | 2/20 | 0.41 |
| ▸ | DAPK1 | P53355 | 2/20 | 0.41 |
| ▸ | CAMK4 | Q16566 | 2/20 | 0.41 |
| ▸ | MAPK15 | Q8TD08 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13537612 | 0.88 | PIM2 (0.58) | PIM2PIM1PIM3NR1H4MEN1 | |
| SCHEMBL13537774 | 0.87 | PIM2 (0.57) | PIM2PIM1PIM3NR1H4PIK3CD | |
| SCHEMBL13537613 | 0.82 | PIM2 (0.45) | PIM2PIM1PIM3NR1H4STK17B | |
| SCHEMBL1579004 | 0.82 | PIM2 (0.58) | PIM2PIM1PIM3NR1H4PIK3CD | |
| SCHEMBL12281525 | 0.82 | PIM2 (0.58) | PIM2PIM1PIM3NR1H4PIK3CD | |
| SCHEMBL1579003 | 0.82 | PIM2 (0.58) | PIM2PIM1PIM3NR1H4PIK3CD | |
| SCHEMBL13537960 | 0.81 | PIM2 (0.66) | PIM2PIM1PIM3NR1H4STK17B | |
| SCHEMBL13537913 | 0.78 | NR1H4 (0.39) | PIM2PIM1PIM3NR1H4MEN1 | |
| SCHEMBL13537618 | 0.77 | PIM2 (0.44) | PIM2PIM1PIM3 | |
| SCHEMBL13537625 | 0.76 | PIM2 (0.48) | PIM2PIM1PIM3NR1H4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010001169-A2 | CHEMICAL COMPOUNDS 251 | ASTRAZENECA AB (SE) | 2010-01-07 | — | — | WO | disclosed |