Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 2/20 | 0.36 |
| ▸ | LAP3 | P28838 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.30 |
| ▸ | CA1 | P00915 | 2/20 | 0.30 |
| ▸ | CA2 | P00918 | 2/20 | 0.30 |
| ▸ | CA4 | P22748 | 2/20 | 0.30 |
| ▸ | CA5A | P35218 | 2/20 | 0.30 |
| ▸ | CA7 | P43166 | 2/20 | 0.30 |
| ▸ | CA9 | Q16790 | 2/20 | 0.30 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.30 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14269491 | 0.82 | ANPEP (0.42) | ANPEPLAP3L3MBTL1ALDH1A1DPP8 | |
| SCHEMBL13538049 | 0.78 | ALDH1A1 (0.41) | ANPEPLAP3L3MBTL1ALDH1A1DPP8 | |
| SCHEMBL3364982 | 0.77 | ALDH1A1 (0.42) | ANPEPLAP3ALDH1A1DPP8SRC | |
| SCHEMBL14390657 | 0.77 | ALDH1A1 (0.42) | ANPEPLAP3ALDH1A1DPP8SRC | |
| SCHEMBL13541355 | 0.76 | ANPEP (0.36) | ANPEPLAP3L3MBTL1 | |
| SCHEMBL13538051 | 0.69 | L3MBTL1 (0.52) | ANPEPLAP3L3MBTL1ALDH1A1MEN1 | |
| SCHEMBL13541364 | 0.65 | BTN3A1 (0.41) | ANPEPLAP3L3MBTL1MEN1KMT2A | |
| SCHEMBL10928374 | 0.64 | SRC (0.48) | L3MBTL1ALDH1A1MEN1KMT2ASRC | |
| SCHEMBL6050586 | 0.64 | SRC (0.54) | ANPEPLAP3L3MBTL1ALDH1A1MEN1 | |
| SCHEMBL408802 | 0.63 | SRC (0.52) | L3MBTL1ALDH1A1MEN1KMT2ASRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7649015-B2 | Cellular accumulation of phosphonate analogs of HIV protease inhibitor compounds | GILEAD SCIENCES, INC. (US) | 2010-01-19 | — | — | US | disclosed |
| US-20090029939-A1 | Pre-organized tricyclic integrase inhibitor compounds | GILEAD SCIENCES, INC. | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090029939-A1 | Pre-organized tricyclic integrase inhibitor compounds | MUS81, CDKL4, INTS6 | ANPEP 691/4885LAP3 1817/4885L3MBTL1 164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.