Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.38 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.38 |
| ▸ | GPR183 | P32249 | 1/20 | 0.38 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.37 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12340312 | 0.94 | PTGDR2 (0.44) | P2RX3PTGDR2KDM4EALDH1A1FFAR1 | |
| SCHEMBL13541577 | 0.94 | PTGDR2 (0.44) | P2RX3PTGDR2KDM4EALDH1A1FFAR1 | |
| SCHEMBL12340326 | 0.94 | PTGDR2 (0.44) | P2RX3PTGDR2KDM4EALDH1A1FFAR1 | |
| SCHEMBL12343053 | 0.82 | KDM4E (0.45) | P2RX3KDM4EALDH1A1SMN1; SMN2CFTR | |
| SCHEMBL12343938 | 0.79 | CFTR (0.47) | P2RX3KDM4EALDH1A1SMN1; SMN2CFTR | |
| SCHEMBL12179986 | 0.79 | P2RX3 (0.49) | P2RX3KDM4EALDH1A1SMN1; SMN2CFTR | |
| SCHEMBL12179838 | 0.79 | P2RX3 (0.52) | P2RX3KDM4EALDH1A1SMN1; SMN2CFTR | |
| SCHEMBL12179822 | 0.77 | P2RX3 (0.48) | P2RX3KDM4EALDH1A1SMN1; SMN2CFTR | |
| SCHEMBL12340311 | 0.77 | MAPT (0.47) | P2RX3KDM4EALDH1A1SMN1; SMN2HSP90AA1 | |
| SCHEMBL55686 | 0.75 | P2RX3 (0.49) | P2RX3PTGDR2KDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010011658-A2 | PYROMELLITIC DIIMIDE ORGANIC SEMICONDUCTORS AND DEVICES | THE JOHNS HOPKINS UNIVERSITY (US) | 2010-01-28 | — | — | WO | disclosed |