Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | EP300 | Q09472 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.42 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.40 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | RGS4 | P49798 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12340309 | 0.92 | MAPT (0.48) | P2RX3KDM4EALDH1A1THRBHSP90AA1 | |
| SCHEMBL12179838 | 0.86 | P2RX3 (0.52) | P2RX3KDM4EALDH1A1CHRM5SMN1; SMN2 | |
| SCHEMBL12179822 | 0.85 | P2RX3 (0.48) | P2RX3KDM4EALDH1A1CHRM5SMN1; SMN2 | |
| SCHEMBL12343938 | 0.83 | CFTR (0.47) | P2RX3KDM4EALDH1A1CHRM5SMN1; SMN2 | |
| SCHEMBL55686 | 0.83 | P2RX3 (0.49) | P2RX3KDM4EALDH1A1CHRM5SMN1; SMN2 | |
| SCHEMBL12343053 | 0.81 | KDM4E (0.45) | P2RX3KDM4EALDH1A1CHRM5SMN1; SMN2 | |
| SCHEMBL2184970 | 0.81 | CA12 (0.54) | P2RX3KDM4EALDH1A1CHRM5SMN1; SMN2 | |
| SCHEMBL12340325 | 0.79 | TP53 (0.52) | ALDH1A1SMN1; SMN2THRBRGS4RGS8 | |
| SCHEMBL13541509 | 0.79 | P2RX3 (0.43) | P2RX3KDM4EALDH1A1CHRM5SMN1; SMN2 | |
| SCHEMBL12340311 | 0.75 | MAPT (0.47) | P2RX3KDM4EALDH1A1SMN1; SMN2DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8269215-B2 | Pyromellitic diimide organic semiconductors and devices | THE JOHNS HOPKINS UNIVERSITY (US) | 2012-09-18 | — | — | US | disclosed |
| WO-2011138743-A1 | USE OF PYROMELLITIC DIIMIDES IN ORGANIC ELECTRONICS AND ORGANIC PHOTOVOLTAICS | BASF SE (DE) | 2011-11-10 | — | — | WO | disclosed |
| US-20110163301-A1 | PYROMELLITIC DIIMIDE ORGANIC SEMICONDUCTORS AND DEVICES | THE JOHNS HOPKINS UNIVERSITY (US) | 2011-07-07 | — | — | US | disclosed |
| WO-2010011658-A2 | PYROMELLITIC DIIMIDE ORGANIC SEMICONDUCTORS AND DEVICES | THE JOHNS HOPKINS UNIVERSITY (US) | 2010-01-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110163301-A1 | PYROMELLITIC DIIMIDE ORGANIC SEMICONDUCTORS AND DEVICES | AQP4, FTO, KCNE1 | P2RX3 2915/4885KDM4E 698/4885ALDH1A1 3029/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.