Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.54 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.54 |
| ▸ | NAMPT | P43490 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13544744 | 0.91 | TAS1R3 (0.56) | PPARGTP53LMNARXFP1MAPT | |
| SCHEMBL13544514 | 0.91 | PPARG (0.61) | PPARGTP53LMNARXFP1MAPT | |
| SCHEMBL13544740 | 0.87 | MAPT (0.61) | PPARGTP53LMNARXFP1MAPT | |
| SCHEMBL3524782 | 0.86 | TAS1R3 (0.59) | PPARGTP53LMNARXFP1MAPT | |
| SCHEMBL3527747 | 0.86 | TAS1R3 (0.56) | PPARGTP53LMNARXFP1MAPT | |
| SCHEMBL23985899 | 0.81 | TAS1R3 (0.71) | TP53LMNARXFP1MAPTTAS1R3 | |
| SCHEMBL30305533 | 0.81 | TAS1R3 (0.71) | TP53LMNARXFP1MAPTTAS1R3 | |
| SCHEMBL3530201 | 0.81 | TAS1R3 (0.57) | PPARGTP53LMNARXFP1MAPT | |
| SCHEMBL13544512 | 0.81 | MAPT (0.61) | PPARGTP53LMNARXFP1MAPT | |
| SCHEMBL8759043 | 0.78 | HPGD (0.70) | TP53MAPTTAS1R3TAS1R1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7645771-B2 | CCR5 antagonists as therapeutic agents | SMITHKLINE BEECHAM CORP. (US) | 2010-01-12 | — | — | US | disclosed |
| US-7645771-B2 | CCR5 antagonists as therapeutic agents | SMITHKLINE BEECHAM CORP. (US) | 2010-01-12 | — | — | US | disclosed |