Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.61 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.61 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CTSD | P07339 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL584428 | 0.85 | PHF8 (0.80) | KDM7APHF8KDM2ACNR1CNR2 | |
| SCHEMBL1792763 | 0.78 | — | — | |
| SCHEMBL629814 | 0.78 | — | — | |
| SCHEMBL17047606 | 0.76 | PHF8 (1.00) | KDM7APHF8KDM2AHDAC3HDAC1 | |
| Succinic Acid SCHEMBL18497045 | 0.76 | PHF8 (1.00) | KDM7APHF8KDM2AHDAC3HDAC1 | |
| SCHEMBL50347 | 0.76 | PHF8 (1.00) | KDM7APHF8KDM2AHDAC3HDAC1 | |
| Hydrochloric Acid SCHEMBL28258601 | 0.76 | KDM7A (0.60) | KDM7APHF8KDM2ACNR1CNR2 | |
| Succinic Acid SCHEMBL18497046 | 0.76 | PHF8 (1.00) | KDM7APHF8KDM2AHDAC3HDAC1 | |
| SCHEMBL19439713 | 0.74 | KDM7A (0.58) | KDM7APHF8KDM2ACNR1CNR2 | |
| SCHEMBL3401157 | 0.74 | PHF8 (0.64) | KDM7APHF8KDM2ACNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7645771-B2 | CCR5 antagonists as therapeutic agents | SMITHKLINE BEECHAM CORP. (US) | 2010-01-12 | — | — | US | disclosed |