Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | EPHB4 | P54760 | 5/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ATP4A | P20648 | 2/20 | 0.32 |
| ▸ | ATP4B | P51164 | 2/20 | 0.32 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TNKS | O95271 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13531801 | 0.78 | BTK (0.40) | EPHB4TNKSKDRAURKA | |
| SCHEMBL13531799 | 0.69 | BTK (0.39) | EPHB4TNKSKDRAURKA | |
| SCHEMBL14878017 | 0.68 | BTK (0.33) | EPHB4AURKA | |
| SCHEMBL13547714 | 0.63 | BTK (0.49) | EPHB4 | |
| SCHEMBL13512878 | 0.61 | NR4A2 (0.39) | MEN1KMT2AALDH1A1RAB9AKDM4E | |
| SCHEMBL23175317 | 0.58 | GSK3B (0.71) | MEN1KMT2A | |
| SCHEMBL29488164 | 0.58 | GSK3B (0.71) | MEN1KMT2A | |
| SCHEMBL5408059 | 0.58 | ADORA1 (0.68) | KMT2AADORA2AALDH1A1RAB9AKDM4E | |
| SCHEMBL24096630 | 0.57 | MAPT (0.59) | MEN1KMT2AEPHB4ALDH1A1RAB9A | |
| SCHEMBL15688262 | 0.56 | NUDT1 (0.55) | ADORA2AALDH1A1L3MBTL1TNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010006970-A1 | NOVEL PHENYLIMIDAZOPYRAZINES | F. HOFFMANN-LA ROCHE AG (CH) | 2010-01-21 | — | — | WO | disclosed |