Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 5/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 5/20 | 0.48 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.48 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | STAT1 | P42224 | 1/20 | 0.47 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.42 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.42 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | TOP1 | P11387 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13547834 | 0.85 | STAT3 (0.49) | PDE3BPDE3AP2RY12STAT3STAT1 | |
| SCHEMBL21523873 | 0.83 | STAT3 (0.53) | STAT3STAT1KDM4EPOLB | |
| SCHEMBL585086 | 0.82 | STAT3 (0.55) | STAT3STAT1ABCG2TOP1 | |
| SCHEMBL3554344 | 0.81 | STAT3 (0.44) | PDE3BPDE3AP2RY12STAT3STAT1 | |
| SCHEMBL14038527 | 0.81 | STAT3 (0.51) | STAT3STAT1KDM4EPOLBTSHR | |
| SCHEMBL3554348 | 0.81 | STAT3 (0.43) | PDE3BPDE3AP2RY12STAT3STAT1 | |
| SCHEMBL585094 | 0.80 | STAT3 (0.48) | STAT3STAT1KDM4EPOLB | |
| SCHEMBL584752 | 0.80 | STAT3 (0.50) | STAT3STAT1POLBTOP1 | |
| Hydrochloric Acid SCHEMBL27856204 | 0.80 | STAT3 (0.50) | STAT3STAT1KDM4EPOLBNPSR1 | |
| Exeporfinium SCHEMBL585997 | 0.80 | STAT3 (0.52) | STAT3STAT1ABCG2POLBTOP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7649091-B2 | complex comprising manganese acetate and {[{(Porphine-5,15-diyl)bis[cyclopropyl-diyl]}](2-)-N21,N22,N23, N24 }; reduce damage to cells; preventing or arresting free radical associated diseases or conditions; free radical scavengers | EUKARION, INC. (US) | 2010-01-19 | — | — | US | disclosed |
| US-7649091-B2 | complex comprising manganese acetate and {[{(Porphine-5,15-diyl)bis[cyclopropyl-diyl]}](2-)-N21,N22,N23, N24 }; reduce damage to cells; preventing or arresting free radical associated diseases or conditions; free radical scavengers | EUKARION, INC. (US) | 2010-01-19 | — | — | US | disclosed |