Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | STAT1 | P42224 | 1/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 5/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 5/20 | 0.37 |
| ▸ | PDE2A | O00408 | 4/20 | 0.37 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.36 |
| ▸ | TOP1 | P11387 | 3/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 2/20 | 0.34 |
| ▸ | CYCS | P99999 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3554348 | 0.87 | STAT3 (0.43) | STAT3STAT1PDE3BPDE3APDE2A | |
| SCHEMBL13547830 | 0.81 | PDE3B (0.48) | STAT3STAT1PDE3BPDE3AP2RY12 | |
| SCHEMBL13547834 | 0.78 | STAT3 (0.49) | STAT3STAT1PDE3BPDE3AP2RY12 | |
| SCHEMBL21523873 | 0.78 | STAT3 (0.53) | STAT3STAT1 | |
| SCHEMBL585086 | 0.77 | STAT3 (0.55) | STAT3STAT1TOP1CYCS | |
| SCHEMBL584752 | 0.77 | STAT3 (0.50) | STAT3STAT1TOP1 | |
| Exeporfinium SCHEMBL585997 | 0.77 | STAT3 (0.52) | STAT3STAT1TOP1CYCS | |
| Hydrochloric Acid SCHEMBL584371 | 0.76 | STAT3 (0.49) | STAT3STAT1TOP1 | |
| SCHEMBL14038527 | 0.76 | STAT3 (0.51) | STAT3STAT1 | |
| Exeporfinium SCHEMBL5012396 | 0.76 | STAT3 (0.51) | STAT3STAT1TOP1CYCS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7649091-B2 | complex comprising manganese acetate and {[{(Porphine-5,15-diyl)bis[cyclopropyl-diyl]}](2-)-N21,N22,N23, N24 }; reduce damage to cells; preventing or arresting free radical associated diseases or conditions; free radical scavengers | EUKARION, INC. (US) | 2010-01-19 | — | — | US | disclosed |
| US-20060241095-A1 | Orally bioavailable low molecular weight metalloporphyrins as antioxidants | EUKARION, INC. | 2006-10-26 | — | — | US | disclosed |
| EP-1631572-A2 | ORALLY BIOAVAILABLE LOW MOLECULAR WEIGHT METALLOPORPHYRINS AS ANTIOXIDANTS | EUKARION, INC. (US) | 2006-03-08 | — | — | EP | disclosed |
| WO-2005000854-A2 | ORALLY BIOAVAILABLE LOW MOLECULAR WEIGHT METALLOPORPHYRINS AS ANTIOXIDANTS | EUKARION, INC. (US) | 2005-01-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060241095-A1 | Orally bioavailable low molecular weight metalloporphyrins as antioxidants | SLC40A1, HMOX1, SOD1 | STAT3 3232/4885STAT1 3491/4885PDE3B 2098/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.