Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | MYC | P01106 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15257926 | 0.83 | HAAO (0.39) | KDM4EALDH1A1NPC1RAB9AHPGD | |
| SCHEMBL1355180 | 0.81 | ALDH1A1 (0.36) | KDM4ECA12CA1CA2CA7 | |
| SCHEMBL12136924 | 0.79 | KDM4E (0.35) | KDM4EMYCMAPTNCOA1NCOA3 | |
| SCHEMBL12136916 | 0.78 | KDM4E (0.36) | KDM4EMAPTNCOA1NCOA3CA12 | |
| SCHEMBL15322423 | 0.76 | PDE4A (0.44) | KDM4EMYCMAPTPPARGNCOA2 | |
| SCHEMBL2014506 | 0.74 | KDM4E (0.43) | KDM4EMYCMAPTMEN1KMT2A | |
| SCHEMBL1355276 | 0.73 | KDM4E (0.41) | KDM4EMYCMAPTPPARGNCOA2 | |
| SCHEMBL12136989 | 0.73 | KDM4E (0.40) | KDM4EMYCMAPTKMT2ATSHR | |
| SCHEMBL8953225 | 0.73 | KDM4E (0.38) | KDM4EMAPTCA12CA1CA2 | |
| SCHEMBL19330648 | 0.72 | CHRM4 (0.48) | KDM4EMAPTTSHRALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8859592-B2 | Insecticidal compounds | SYNGENTA CORP PROTECTION LLC (US) | 2014-10-14 | — | — | US | disclosed |
| US-8859592-B2 | Insecticidal compounds | SYNGENTA CORP PROTECTION LLC (US) | 2014-10-14 | — | — | US | disclosed |
| US-8859592-B2 | Insecticidal compounds | SYNGENTA CORP PROTECTION LLC (US) | 2014-10-14 | — | — | US | disclosed |
| US-20130245072-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CORP PROTECTION LLC (US) | 2013-09-19 | — | — | US | disclosed |
| US-20130245072-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CORP PROTECTION LLC (US) | 2013-09-19 | — | — | US | disclosed |
| US-20130245072-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CORP PROTECTION LLC (US) | 2013-09-19 | — | — | US | disclosed |
| US-20110288089-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2011-11-24 | — | — | US | disclosed |
| US-20110288089-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2011-11-24 | — | — | US | disclosed |
| US-20110288089-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2011-11-24 | — | — | US | disclosed |
| EP-2379541-A2 | INSECTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2011-10-26 | — | — | EP | disclosed |
| WO-2010084067-A2 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2010-07-29 | — | — | WO | disclosed |
| WO-2010084067-A2 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2010-07-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110288089-A1 | INSECTICIDAL COMPOUNDS | ACHE, CHRM1, CHRM2 | KDM4E 3205/4885MYC 4843/4885MAPT 3636/4885 |
| US-20130245072-A1 | INSECTICIDAL COMPOUNDS | ACHE, CHRM1, CHRM2 | KDM4E 3205/4885MYC 4843/4885MAPT 3636/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.