SCHEMBL13548355

SCHEMBL13548355

Cc1ccc(-c2c(O)cc(C3CCC(C)CO3)cc2O)cc1

nearest known ligand 0.32

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 1/20 0.32
TAS1R1 Q7RTX1 1/20 0.32
TAS1R2 Q8TE23 1/20 0.32
ALOX15 P16050 1/20 0.32
ALOX12 P18054 1/20 0.32
CNR1 P21554 1/20 0.32
CNR2 P34972 1/20 0.32
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32
BCL9 O00512 1/20 0.31
CTNNB1 P35222 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14087908 0.87 ALOX15 (0.33) ALOX15ALOX12CNR1CNR2BCL9
SCHEMBL91769 0.84 MAOB (0.32) MAOB
SCHEMBL82500 0.84
SCHEMBL14087897 0.84 BRD4 (0.36)
SCHEMBL82063 0.81 ACHE (0.34)
SCHEMBL12754474 0.78 TSHR (0.39) ALOX12MAOB
SCHEMBL12829104 0.78 TSHR (0.39) ALOX12MAOB
SCHEMBL12754470 0.78 TSHR (0.39) ALOX12MAOB
SCHEMBL83121 0.78
SCHEMBL14087901 0.77 ERN1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1658350-B1 COMPOUNDS FOR USE IN LIQUID CRYSTAL MEDIA MERCK PATENT GMBH (DE) 2010-01-20 EP disclosed