⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16492042 | 0.73 | — | — | |
| SCHEMBL16367926 | 0.72 | DHFR (0.43) | — | |
| SCHEMBL8179011 | 0.70 | — | — | |
| SCHEMBL22475100 | 0.67 | DHFR (0.33) | — | |
| SCHEMBL24667242 | 0.66 | — | — | |
| SCHEMBL8179007 | 0.64 | ADRA2C (0.35) | — | |
| SCHEMBL12522818 | 0.62 | DHFR (0.37) | — | |
| SCHEMBL16918403 | 0.61 | DHFR (0.33) | — | |
| SCHEMBL18903734 | 0.60 | — | — | |
| SCHEMBL2043527 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9815864-B2 | Substituted nucleosides, nucleotides and analogs thereof | ALIOS BIOPHARMA, INC. (US) | 2017-11-14 | — | — | US | disclosed |
| US-20150284783-A1 | METHODS AND COMPOSITIONS FOR ANALYZING NUCLEIC ACID | AGENA BIOSCIENCE, INC. | 2015-10-08 | — | — | US | disclosed |
| US-20150011497-A1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | Janssen Pharmaceuticals, Inc. | 2015-01-08 | — | — | US | disclosed |
| US-20100016250-A1 | TOLL-LIKE RECEPTOR 9 AGONISTS | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2010-01-21 | — | — | US | disclosed |
| US-20100016250-A1 | TOLL-LIKE RECEPTOR 9 AGONISTS | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2010-01-21 | — | — | US | disclosed |
| US-7312038-B2 | Photocleavable bioreactive agents | THE TRUSTEES OF BOSTON UNIVERSITY (US) | 2007-12-25 | — | — | US | disclosed |
| US-7195874-B2 | Detecting targets in heterologous mixtures | THE TRUSTEES OF BOSTON UNIVERSITY (US) | 2007-03-27 | — | — | US | disclosed |
| US-20070020643-A1 | Photocleavable bioreactive agents | THE TRUSTEES OF BOSTON UNIVERSITY (US) | 2007-01-25 | — | — | US | disclosed |