SCHEMBL1355010

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4655445	0.91	SIGMAR1 (0.55)	SIGMAR1HTR2BKMT2ALMNASMARCA2
	SCHEMBL1356396	0.83	SIGMAR1 (0.67)	SIGMAR1
	SCHEMBL1356487	0.81	SIGMAR1 (0.57)	SIGMAR1HTR2BKMT2ALMNATSHR
	SCHEMBL31466529	0.80	SIGMAR1 (0.67)	SIGMAR1HTR2B
	SCHEMBL1357638	0.80	SIGMAR1 (0.71)	SIGMAR1HTR2BKMT2ALMNASMARCA2
	SCHEMBL4654496	0.79	SIGMAR1 (0.62)	SIGMAR1HTR2BKMT2ALMNASMARCA2
	SCHEMBL1740562	0.79	SIGMAR1 (0.76)	SIGMAR1HTR2B
	SCHEMBL29371513	0.78	SIGMAR1 (1.00)	SIGMAR1HTR2B
	SCHEMBL99404	0.78	SIGMAR1 (1.00)	SIGMAR1HTR2B
	Hydrochloric Acid SCHEMBL99116	0.77	SIGMAR1 (0.98)	SIGMAR1HTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.