Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.93 |
| ▸ | AKR1B10 | O60218 | 7/20 | 0.90 |
| ▸ | AKR1B1 | P15121 | 7/20 | 0.90 |
| ▸ | CA12 | O43570 | 5/20 | 0.90 |
| ▸ | CA7 | P43166 | 5/20 | 0.90 |
| ▸ | CA9 | Q16790 | 5/20 | 0.90 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.90 |
| ▸ | CA4 | P22748 | 4/20 | 0.90 |
| ▸ | CA6 | P23280 | 4/20 | 0.90 |
| ▸ | CA5A | P35218 | 4/20 | 0.90 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.90 |
| ▸ | TTR | P02766 | 2/20 | 0.75 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.69 |
| ▸ | MAOB | P27338 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | GSK3B | P49841 | 2/20 | 0.58 |
| ▸ | BACE1 | P56817 | 2/20 | 0.58 |
| ▸ | CA1 | P00915 | 3/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzyl Cinnamate SCHEMBL43213 | 0.96 | LMNA (1.00) | LMNAAKR1B10AKR1B1CA12CA7 | |
| Benzyl Cinnamate SCHEMBL1871854 | 0.96 | LMNA (1.00) | LMNAAKR1B10AKR1B1CA12CA7 | |
| Benzyl Cinnamate SCHEMBL901152 | 0.96 | LMNA (1.00) | LMNAAKR1B10AKR1B1CA12CA7 | |
| Benzyl Cinnamate SCHEMBL43212 | 0.96 | LMNA (1.00) | LMNAAKR1B10AKR1B1CA12CA7 | |
| SCHEMBL4501585 | 0.95 | AKR1B10 (1.00) | LMNAAKR1B10AKR1B1CA12CA7 | |
| SCHEMBL22071063 | 0.95 | LMNA (0.84) | LMNAAKR1B10AKR1B1CA12CA7 | |
| SCHEMBL4501587 | 0.95 | AKR1B10 (1.00) | LMNAAKR1B10AKR1B1CA12CA7 | |
| SCHEMBL15419990 | 0.95 | AKR1B10 (1.00) | LMNAAKR1B10AKR1B1CA12CA7 | |
| SCHEMBL29641956 | 0.94 | LMNA (0.82) | LMNAAKR1B10AKR1B1CA12CA7 | |
| SCHEMBL890443 | 0.94 | LMNA (0.82) | LMNAAKR1B10AKR1B1CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010006889-A2 | COUPLING AGENTS FOR FILLED RUBBERS | BASF SE (DE) | 2010-01-21 | — | — | WO | disclosed |