Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16405374 | 1.00 | GRIK1 (0.33) | GRIK1GRIK2CTSK | |
| SCHEMBL14296323 | 1.00 | GRIK1 (0.33) | GRIK1GRIK2CTSK | |
| SCHEMBL9090285 | 0.85 | MEN1 (0.33) | GRIK1GRIK2CTSK | |
| SCHEMBL9547937 | 0.85 | MEN1 (0.33) | GRIK1GRIK2CTSK | |
| SCHEMBL16072763 | 0.83 | GRIK1 (0.35) | GRIK1GRIK2 | |
| SCHEMBL16841347 | 0.82 | CTSK (0.32) | GRIK1GRIK2CTSK | |
| SCHEMBL16841348 | 0.82 | CTSK (0.32) | GRIK1GRIK2CTSK | |
| SCHEMBL18501473 | 0.81 | GRIK1 (0.32) | GRIK1GRIK2CTSK | |
| SCHEMBL18969756 | 0.81 | GRIK1 (0.32) | GRIK1GRIK2CTSK | |
| SCHEMBL18501471 | 0.81 | GRIK1 (0.32) | GRIK1GRIK2CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120270934-A1 | PROSTACYCLIN DERIVATIVES | CONCERT PHARMACEUTICALS, INC. | 2012-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120270934-A1 | PROSTACYCLIN DERIVATIVES | PTGIS, PTGIR, PTGER1 | GRIK1 2830/4885GRIK2 3363/4885CTSK 4403/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.