Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 2/20 | 0.44 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.44 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 6/20 | 0.44 |
| ▸ | AR | P10275 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13768718 | 0.85 | AR (0.45) | SHBGSERPINA6SLC22A1ALDH1A1THRB | |
| SCHEMBL13796510 | 0.83 | PGR (0.47) | SHBGSERPINA6SLC22A1ALDH1A1THRB | |
| SCHEMBL13796902 | 0.78 | PGR (0.34) | PGRAR | |
| SCHEMBL13768826 | 0.75 | — | — | |
| SCHEMBL13796904 | 0.75 | PGR (0.37) | PGRARSLC6A4NR3C1NR3C2 | |
| SCHEMBL13768840 | 0.75 | PGR (0.36) | PGRARSLC6A4NR3C1 | |
| SCHEMBL3768432 | 0.74 | PGR (0.54) | SHBGSERPINA6SLC22A1ALDH1A1THRB | |
| SCHEMBL13796898 | 0.73 | AR (0.32) | ALDH1A1ARCYP3A4 | |
| SCHEMBL3763087 | 0.72 | PGR (0.58) | SHBGSERPINA6SLC22A1ALDH1A1THRB | |
| SCHEMBL13769023 | 0.72 | PGR (0.43) | SHBGSERPINA6SLC22A1ALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2238150-B1 | 15,16-METHYLENE-17-HYDROXY-19-NOR-21-CARBOXYLIC ACID y-LACTONE DERIVATIVE, USE THEREOF, AND MEDICAMENT CONTAINING SAID DERIVATIVE | BAYER IP GMBH (DE) | 2012-10-24 | — | — | EP | disclosed |