Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13556656 | 0.73 | SHBG (0.44) | ARCYP3A4ALDH1A1 | |
| SCHEMBL13796902 | 0.72 | PGR (0.34) | AR | |
| SCHEMBL13796510 | 0.70 | PGR (0.47) | ARCYP3A4ALDH1A1 | |
| SCHEMBL13768718 | 0.70 | AR (0.45) | ARALDH1A1 | |
| SCHEMBL13768826 | 0.66 | — | — | |
| SCHEMBL13769023 | 0.64 | PGR (0.43) | ARCYP3A4ALDH1A1 | |
| SCHEMBL13796904 | 0.64 | PGR (0.37) | AR | |
| SCHEMBL13768840 | 0.64 | PGR (0.36) | AR | |
| SCHEMBL13342047 | 0.61 | AR (0.33) | ARHIF1A | |
| SCHEMBL13768466 | 0.59 | CYP19A1 (0.37) | ARCYP3A4CYP2C9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083269-A1 | 15,16-METHYLENE-17-HYDROXY-19-NOR-21-CARBOXYLIC ACID γ-LACTONE DERIVATIVE, USE THEREOF, AND MEDICAMENT CONTAINING SAID DERIVATIVE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-09 | — | — | WO | disclosed |