Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | NCEH1 | Q6PIU2 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12950974 | 0.87 | LMNA (0.35) | LMNAPLAUGPBAR1NR1H3 | |
| SCHEMBL998644 | 0.80 | DHODH (0.46) | DHODHHPGDPLAUMEN1KMT2A | |
| SCHEMBL12950948 | 0.77 | DHODH (0.36) | LMNADHODHHPGDPLAUKMT2A | |
| SCHEMBL29409942 | 0.69 | NR1H3 (0.54) | LMNAGPBAR1NR1H3KMT2A | |
| SCHEMBL15429580 | 0.69 | HPGD (0.47) | HPGDGPBAR1NR1H3MEN1KMT2A | |
| SCHEMBL12951216 | 0.67 | MAPT (0.38) | DHODHHPGDPLAUMEN1KMT2A | |
| SCHEMBL1844491 | 0.67 | PTGS1 (0.44) | LMNAGPBAR1NR1H3MEN1KMT2A | |
| SCHEMBL18726192 | 0.66 | DHODH (0.50) | LMNADHODHPLAU | |
| SCHEMBL12659386 | 0.65 | GPBAR1 (0.40) | GPBAR1NR1H3 | |
| SCHEMBL19240535 | 0.65 | GPBAR1 (0.38) | LMNAGPBAR1NR1H3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2456759-B1 | PESTICIDAL CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2017-04-19 | — | — | EP | disclosed |
| US-8822691-B2 | Pesticidal carboxamides | BAYER CROPSCIENCE AG (DE) | 2014-09-02 | — | — | US | disclosed |
| US-8822691-B2 | Pesticidal carboxamides | BAYER CROPSCIENCE AG (DE) | 2014-09-02 | — | — | US | disclosed |
| US-20120277185-A1 | Pesticidal Carboxamides | BAYER CROPSCIENDE AG (DE) | 2012-11-01 | — | — | US | disclosed |
| US-20120277185-A1 | Pesticidal Carboxamides | BAYER CROPSCIENDE AG (DE) | 2012-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120277185-A1 | Pesticidal Carboxamides | DDT, ACHE, AADAC | LMNA 3905/4885L3MBTL1 535/4885DHODH 750/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.