SCHEMBL1355987

SCHEMBL1355987

O=C(O)CNCCNCC(=O)O.[NaH].[NaH]

nearest known ligand 0.48

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.41
LDHA P00338 1/20 0.41
SRR Q9GZT4 1/20 0.41
ALKBH5 Q6P6C2 1/20 0.41
SUCNR1 Q9BXA5 1/20 0.41
EGLN1 Q9GZT9 1/20 0.41
CA1 P00915 9/20 0.40
CA2 P00918 9/20 0.40
TSHR P16473 1/20 0.39
SLC22A6 Q4U2R8 1/20 0.37
CTH P32929 1/20 0.36
LTA4H P09960 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1644077 1.00 LMNA (0.41) LMNALDHASRRALKBH5SUCNR1
SCHEMBL163217 0.97 LMNA (0.44) LMNALDHASRRALKBH5SUCNR1
SCHEMBL10988936 0.97 LMNA (0.44) LMNALDHASRRALKBH5SUCNR1
SCHEMBL1134677 0.93 LMNA (0.41) LMNALDHASRRALKBH5SUCNR1
SCHEMBL18160753 0.93 LMNA (0.41) LMNALDHASRRALKBH5SUCNR1
SCHEMBL6343644 0.93 LMNA (0.41) LMNALDHASRRALKBH5SUCNR1
Water SCHEMBL4057424 0.93 LMNA (0.41) LMNALDHASRRALKBH5SUCNR1
SCHEMBL1684976 0.93 LMNA (0.41) LMNALDHASRRALKBH5SUCNR1
SCHEMBL8186348 0.88 LMNA (0.44) LMNALDHASRRALKBH5SUCNR1
SCHEMBL10608338 0.87 CAMK2A (0.36) LMNALDHASRRALKBH5SUCNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9012684-B2 Aminocarboxylate powders with improved purity and flowability properties DOW GLOBAL TECHNOLOGIES LLC 2015-04-21 US claimed
EP-2571846-A2 AMINOCARBOXYLATE POWDERS WITH IMPROVED PURITY AND FLOW ABILITY PROPERTIES Dow Global Technologies LLC (US) 2013-03-27 EP claimed
US-20110288332-A1 AMINOCARBOXYLATE POWDERS WITH IMPROVED PURITY AND FLOWABILITY PROPERTIES DOW GLOBAL TECHNOLOGIES LLC 2011-11-24 US claimed
WO-2011146582-A2 AMINOCARBOXYLATE POWDERS WITH IMPROVED PURITY AND FLOW ABILITY PROPERTIES DOW GLOBAL TECHNOLOGIES LLC. (US) 2011-11-24 WO claimed
EP-3848349-B1 A PROCESS FOR THE PREPARATION OF SALTS OF N,N'-DISUBSTITUTED ETHYLENEDIAMINE-N,N'-DIACETIC ACID DERIVATIVES AND THEIR USE PRZED PRODUKCYJNO CONSULTINGOWE ADOB SP Z O O (PL) 2023-03-15 EP disclosed
EP-3848349-A1 A PROCESS FOR THE PREPARATION OF SALTS OF N,N'-DISUBSTITUTED ETHYLENEDIAMINE-N,N'-DIACETIC ACID DERIVATIVES AND THEIR USE Przedsiebiorstwo Produkcyjno-Consultingowe ADOB Sp. z o.o. Sp. jawna (PL) 2021-07-14 EP disclosed
EP-1861486-B1 A PROCESS OF PREPARING JAMBU EXTRACT, USE OF SAID EXTRACT, COSMETIC COMPOSITIONS COMPRISING THEREOF AND COSMETIC PRODUCTS COMPRISING SAID COSMETIC COMPOSITIONS NATURA COSMETICOS SA (BR) 2017-05-17 EP disclosed
US-9056089-B2 Process of preparing jambu extract, use of said extract, cosmetic compositions comprising thereof and cosmetic products comprising said cosmetic compositions NATURA COSMETICOS S.A. (BR) 2015-06-16 US disclosed
EP-2743254-A1 Method for preparing an aminocarboxylate chelant containing low level of nitrilotriacetic acid Dow Global Technologies LLC (US) 2014-06-18 EP disclosed
US-20080171003-A1 free from chlorophyll and its derivatives; by selective basic hydrolysis of chlorophyll; high yield, simplification; extracts of spilanthol NATURA COSMETICOS S.A. (BR) 2008-07-17 US disclosed
US-4051234-A BIS-GUANIDINE COMPOUND, ETHYLENEDIAMINEDIACETIC ACID OR SALT AS CHELATOR THE PROCTER & GAMBLE COMPANY (US) 1977-09-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080171003-A1 free from chlorophyll and its derivatives; by selective basic hydrolysis of chlorophyll; high yield, simplification; extracts of spilanthol TYR, HMBS, NISCH LMNA 1505/4885LDHA 2114/4885SRR 589/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.