SCHEMBL1356073

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3585927	0.92	STAT6 (0.53)	STAT6PLK4CDK4CCND3CCND1
	SCHEMBL3587747	0.90	CDK4 (0.51)	STAT6CDK4CCND3CCND1CCND2
	SCHEMBL3586411	0.83	SRC (0.40)	CDK4CCND3CCND1CCND2CCNA2
	SCHEMBL3588808	0.82	CDK4 (0.54)	STAT6CDK4CCND3CCND1CCND2
	SCHEMBL3571516	0.82	EGFR (0.56)	CDK4CCND3CCND1CCND2CCNA2
	SCHEMBL1355881	0.82	STAT6 (0.57)	STAT6PLK4CDK4CCND3CCND1
	SCHEMBL3579319	0.80	GSK3B (0.50)	AURKAAURKBJAK2
	SCHEMBL1355974	0.79	DCLK1 (0.46)	CDK4CCND3CCND1CCND2CCNA2
	SCHEMBL1356168	0.79	STAT6 (0.57)	STAT6PLK4CDK4CCND3CCND1
	SCHEMBL1355600	0.77	SYK (0.54)	STAT6PLK4CDK4CCND3CCND1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.