SCHEMBL1355881

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1353840	0.89	CDK4 (0.54)	STAT6JAK2MAPK8MAPK10CDK4
	SCHEMBL1355286	0.89	CDK4 (0.59)	JAK2CDK4CCND3CCND1CCND2
	SCHEMBL3585927	0.85	STAT6 (0.53)	STAT6JAK2IGF1RCDK4CCND3
	SCHEMBL1356073	0.82	STAT6 (0.50)	STAT6JAK2JUNMAPK8MAPK10
	SCHEMBL1353745	0.80	AURKA (0.53)	JAK2AURKAAURKB
	SCHEMBL1355600	0.79	SYK (0.54)	STAT6IGF1RCDK4CCND3CCND1
	SCHEMBL16513631	0.79	MAPK10 (0.79)	STAT6JAK2JUNMAPK8MAPK10
	SCHEMBL29847439	0.79	MAPK10 (0.79)	STAT6JAK2JUNMAPK8MAPK10
	SCHEMBL3583463	0.78	CDK4 (0.52)	STAT6JAK2IGF1RCDK4CCND3
	SCHEMBL1353795	0.78	DCLK1 (0.52)	CDK4CCND3CCND1CCND2AURKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.