Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SNCA | P37840 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.35 |
| ▸ | RHOA | P61586 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21063734 | 0.85 | MEN1 (0.51) | MEN1KMT2ASNCACYP3A4ALDH1A1 | |
| SCHEMBL13563231 | 0.85 | MEN1 (0.51) | MEN1KMT2ASNCACYP3A4ALDH1A1 | |
| SCHEMBL1461229 | 0.83 | MEN1 (0.54) | MEN1KMT2ASNCACYP3A4ALDH1A1 | |
| SCHEMBL8055864 | 0.80 | MEN1 (0.54) | MEN1KMT2ASNCACYP3A4ALDH1A1 | |
| SCHEMBL23537696 | 0.79 | MEN1 (0.53) | MEN1KMT2ASNCACYP3A4ALDH1A1 | |
| SCHEMBL10664482 | 0.79 | KMT2A (0.53) | MEN1KMT2ASNCACYP3A4ALDH1A1 | |
| SCHEMBL2661626 | 0.79 | MEN1 (0.53) | MEN1KMT2ASNCACYP3A4ALDH1A1 | |
| SCHEMBL13563235 | 0.79 | MEN1 (0.53) | MEN1KMT2ASNCACYP3A4ALDH1A1 | |
| SCHEMBL30013699 | 0.79 | MEN1 (0.53) | MEN1KMT2ASNCACYP3A4ALDH1A1 | |
| SCHEMBL14802855 | 0.78 | KMT2A (0.53) | MEN1KMT2ASNCACYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8575144-B2 | Beta-lactamase inhibitory compounds | SOUTHERN METHODIST UNIVERSITY (US) | 2013-11-05 | — | — | US | disclosed |
| US-20130079318-A1 | BETA-LACTAMASE INHIBITORY COMPOUNDS | SOUTHERN METHODIST UNIVERSITY (US) | 2013-03-28 | — | — | US | disclosed |
| US-8299051-B2 | Beta-lactamase inhibitory compounds | SOUTHERN METHODIST UNIVERSITY (US) | 2012-10-30 | — | — | US | disclosed |
| US-8299051-B2 | Beta-lactamase inhibitory compounds | SOUTHERN METHODIST UNIVERSITY (US) | 2012-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130079318-A1 | BETA-LACTAMASE INHIBITORY COMPOUNDS | MGAM, GUSB, LCT | MEN1 3447/4885KMT2A 2964/4885SNCA 2404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.