⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19859960 | 0.83 | L3MBTL1 (0.36) | — | |
| SCHEMBL19902013 | 0.77 | OGA (0.39) | — | |
| SCHEMBL13563735 | 0.77 | OGA (0.39) | — | |
| SCHEMBL21530603 | 0.77 | OGA (0.39) | — | |
| SCHEMBL11915783 | 0.77 | OGA (0.39) | — | |
| SCHEMBL19631197 | 0.77 | LGALS8 (0.41) | — | |
| SCHEMBL19631324 | 0.77 | LGALS8 (0.41) | — | |
| SCHEMBL21122324 | 0.77 | OGA (0.39) | — | |
| SCHEMBL27332925 | 0.76 | L3MBTL1 (0.33) | — | |
| SCHEMBL17986845 | 0.76 | L3MBTL1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160346421-A1 | APTAMER-MODIFIED POLYMERIC MATERIALS FOR THE BINDING OF FACTORS IN A WOUND ENVIRONMENT | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY | 2016-12-01 | — | — | US | disclosed |
| US-9382290-B2 | Aptamer-modified polymeric materials for the binding of factors in a wound environment | KCI LICENSING, INC. (US) | 2016-07-05 | — | — | US | disclosed |
| US-20120276039-A1 | APTAMER-MODIFIED POLYMERIC MATERIALS FOR THE BINDING OF FACTORS IN A WOUND ENVIRONMENT | KCI LICENSING, INC. (US) | 2012-11-01 | — | — | US | disclosed |