Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13564773 | 0.87 | L3MBTL1 (0.48) | POLBCYP1A2ALDH1A1KMT2AMAPT | |
| SCHEMBL17090328 | 0.86 | PRSS1 (0.42) | POLBHPGDCA1CA2CA12 | |
| SCHEMBL10113440 | 0.85 | ALDH1A1 (0.54) | POLBSMN1; SMN2MAPK1CA1CA2 | |
| SCHEMBL13565821 | 0.82 | ALDH1A1 (0.49) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL13565283 | 0.82 | ALDH1A1 (0.50) | SMN1; SMN2MAPK1ALDH1A1KMT2AMAPT | |
| SCHEMBL13565331 | 0.82 | CA1 (0.37) | POLBCA1CA2ALDH1A1KMT2A | |
| SCHEMBL11934900 | 0.82 | MAPT (0.46) | POLBSMN1; SMN2MAPK1ALDH1A1KMT2A | |
| SCHEMBL11697079 | 0.82 | SMN1; SMN2 (0.59) | POLBSMN1; SMN2HPGDCA1CA2 | |
| SCHEMBL13564864 | 0.81 | EPHX1 (0.39) | SMN1; SMN2CA1CA2ALDH1A1KMT2A | |
| SCHEMBL11935535 | 0.81 | CA1 (0.48) | CA1CA2CA12CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |
| US-8299265-B2 | Amine derivatives having NPY Y5 receptor antagonistic activity and the uses thereof | SHIONOGI & CO., LTD. (JP) | 2012-10-30 | — | — | US | disclosed |