Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 6/20 | 0.62 |
| ▸ | AKR1C2 | P52895 | 6/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | GRM8 | O00222 | 1/20 | 0.45 |
| ▸ | GRM6 | O15303 | 1/20 | 0.45 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31718130 | 1.00 | AKR1C3 (0.62) | AKR1C3AKR1C2NPC1ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL10484221 | 0.98 | AKR1C3 (0.61) | AKR1C3AKR1C2NPC1ALDH1A1MEN1 | |
| Nitrobenzene SCHEMBL28691684 | 0.95 | AKR1C3 (0.58) | AKR1C3AKR1C2NPC1ALDH1A1MEN1 | |
| SCHEMBL11563897 | 0.91 | AKR1C3 (0.55) | AKR1C3AKR1C2NPC1ALDH1A1MEN1 | |
| SCHEMBL1527805 | 0.87 | AKR1C3 (0.50) | AKR1C3AKR1C2NPC1ALDH1A1MEN1 | |
| SCHEMBL7733304 | 0.85 | NPC1 (0.50) | AKR1C3AKR1C2NPC1ALDH1A1MEN1 | |
| SCHEMBL6462715 | 0.85 | TSHR (0.49) | AKR1C3AKR1C2NPC1ALDH1A1MEN1 | |
| SCHEMBL5742182 | 0.85 | ALDH1A1 (0.49) | AKR1C3AKR1C2NPC1ALDH1A1MEN1 | |
| SCHEMBL12814779 | 0.84 | ALDH1A1 (0.50) | AKR1C3AKR1C2NPC1ALDH1A1MEN1 | |
| SCHEMBL30728436 | 0.84 | BCL9 (0.73) | AKR1C3AKR1C2NPC1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 644 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120888531-B | Method for synthesizing indobufen intermediate 2- (4-nitrophenyl) butyric acid by using enzymatic method | PEKING UNIVERSITY THIRD HOSPITAL (PEKING UNIVERSITY THIRD CLINICAL MEDICAL COLLEGE) (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-118978445-A | Method for synthesizing indobufen intermediate 2- (4-nitrophenyl) butyric acid | 陕西西岳制药(扶风)有限公司 | 2024-11-19 | — | — | CN | claimed |
| CN-118724737-A | Preparation method of indobufen and intermediate thereof | 福安药业集团重庆博圣制药有限公司 | 2024-10-01 | — | — | CN | claimed |
| CN-114940649-B | Method for synthesizing indobufen intermediate 2- (4-nitrophenyl) butyric acid | 大连万福制药有限公司 | 2024-07-09 | — | — | CN | claimed |
| CN-114516799-B | Synthesis method of indobufen key intermediate 2- (4-nitrophenyl) butyric acid | 杭州中美华东制药有限公司 | 2024-02-20 | — | — | CN | claimed |
| CN-117263842-A | Preparation method of indobufen | 浙江工业大学 | 2023-12-22 | — | — | CN | claimed |
| EP-3696264-B1 | COMPOSITIONS AND METHODS COMPRISING A LIPOLYTIC ENZYME VARIANT | DANISCO US INC (US) | 2023-06-28 | — | — | EP | claimed |
| CN-116338022-A | Method for analyzing related substances in indobufen starting material 1 | 湖南九典制药股份有限公司 | 2023-06-27 | — | — | CN | claimed |
| CN-116143643-A | Preparation method of 2- (4-aminophenyl) butyric acid | 赤峰经方医药技术开发有限责任公司 | 2023-05-23 | — | — | CN | claimed |
| CN-114940649-A | Method for synthesizing indobufen intermediate 2- (4-nitrophenyl) butyric acid | 大连万福制药有限公司 | 2022-08-26 | — | — | CN | claimed |
| CN-111386331-A | Ester compound, lubricating oil composition containing same, and method for producing same | 埃克森美孚化学专利公司 | 2020-07-07 | — | — | CN | claimed |
| EP-3022299-B1 | COMPOSITIONS AND METHODS COMPRISING A LIPOLYTIC ENZYME VARIANT | DANISCO US INC (US) | 2020-03-18 | — | — | EP | claimed |
| US-20190100710-A1 | Ester Compounds, Lubricating Oil Compositions Containing Same and Processes for Making Same | EXXONMOBIL CHEMICAL PATENTS INC. | 2019-04-04 | — | — | US | claimed |
| WO-2019067061-A1 | ESTER COMPOUNDS, LUBRICATING OIL COMPOSITIONS CONTAINING SAME AND PROCESSES FOR MAKING SAME | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2019-04-04 | — | — | WO | claimed |
| US-8623996-B2 | Cold active enzyme and method thereof | UNIVERSITY PUTRA MALAYSIA (MY) | 2014-01-07 | — | — | US | claimed |
| US-20120058514-A1 | COLD ACTIVE ENZYME AND METHOD THEREOF | UNIVERSITY PUTRA MALAYSIA (MY) | 2012-03-08 | — | — | US | claimed |
| US-20120058527-A1 | CAL A-RELATED ACYLTRANSFERASES AND METHODS OF USE, THEREOF | DANISCO US INC. (US) | 2012-03-08 | — | — | US | claimed |
| US-20090128771-A1 | FABRICATION METHODS FOR LIQUID CRYSTAL DISPLAY DEVICES | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2009-05-21 | — | — | US | claimed |
| EP-0897942-B1 | A method of crosslinking collagen-based material and bioprosthetic devices produced therefrom | MEDTRONIC INC (US) | 2004-03-10 | — | — | EP | claimed |
| EP-0268452-B1 | NOVEL HYDROLASE AND METHOD OF PRODUCTION | GENENCOR, INC. (US) | 1992-01-22 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190100710-A1 | Ester Compounds, Lubricating Oil Compositions Containing Same and Processes for Making Same | ELOVL1, NOTUM, ELOVL5 | AKR1C3 1532/4885AKR1C2 972/4885NPC1 546/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.