Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 3/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 8/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 4/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13564973 | 1.00 | GRIA1 (0.40) | GRIA1NPY5RKDM4ELMNABRD4 | |
| SCHEMBL17090058 | 1.00 | GRIA1 (0.40) | GRIA1NPY5RKDM4ELMNABRD4 | |
| SCHEMBL17090277 | 0.91 | GRIA1 (0.37) | GRIA1NPY5RKDM4ELMNABRD4 | |
| SCHEMBL13565977 | 0.91 | GRIA1 (0.37) | GRIA1NPY5RKDM4ELMNABRD4 | |
| SCHEMBL13564950 | 0.87 | GRIA1 (0.39) | GRIA1NPY5RKDM4ELMNABRD4 | |
| SCHEMBL17090285 | 0.86 | GRIA1 (0.36) | GRIA1NPY5R | |
| SCHEMBL13565798 | 0.86 | GRIA1 (0.36) | GRIA1NPY5R | |
| SCHEMBL11935630 | 0.85 | NPY5R (0.35) | NPY5RKDM4ELMNABRD4 | |
| SCHEMBL11941032 | 0.85 | NPY5R (0.35) | NPY5RKDM4ELMNABRD4 | |
| SCHEMBL10115309 | 0.85 | KMT2A (0.40) | GRIA1KDM4ELMNAHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8299265-B2 | Amine derivatives having NPY Y5 receptor antagonistic activity and the uses thereof | SHIONOGI & CO., LTD. (JP) | 2012-10-30 | — | — | US | disclosed |