Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.44 |
| ▸ | CNR2 | P34972 | 7/20 | 0.36 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.34 |
| ▸ | ULK1 | O75385 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17090302 | 1.00 | GPR119 (0.44) | GPR119CNR2BAZ2BMKNK1MAPK14 | |
| SCHEMBL13565002 | 0.85 | GPR119 (0.40) | GPR119BAZ2BMKNK1MAPK14NPY5R | |
| SCHEMBL13438769 | 0.83 | SMN1; SMN2 (0.40) | CNR2ALDH1A1ALDH3A1 | |
| SCHEMBL11934887 | 0.83 | SMN1; SMN2 (0.40) | CNR2ALDH1A1ALDH3A1 | |
| SCHEMBL17090320 | 0.81 | PARG (0.46) | CNR2ALDH1A1ALDH3A1 | |
| SCHEMBL13565643 | 0.81 | PARG (0.46) | CNR2ALDH1A1ALDH3A1 | |
| SCHEMBL17090114 | 0.80 | CNR2 (0.52) | CNR2ALDH1A1 | |
| SCHEMBL13565145 | 0.80 | CNR2 (0.52) | CNR2ALDH1A1 | |
| SCHEMBL10133710 | 0.80 | MAPK14 (0.53) | GPR119BAZ2BMAPK14NPY5RALDH1A1 | |
| SCHEMBL13203799 | 0.80 | MAPK14 (0.53) | GPR119BAZ2BMAPK14NPY5RALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8299265-B2 | Amine derivatives having NPY Y5 receptor antagonistic activity and the uses thereof | SHIONOGI & CO., LTD. (JP) | 2012-10-30 | — | — | US | disclosed |