Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | WDR5 | P61964 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17090447 | 1.00 | KMT2A (0.38) | KMT2ALMNAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL13113663 | 0.87 | KDM4E (0.37) | KMT2ALMNAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL13105264 | 0.87 | KDM4E (0.37) | KMT2ALMNAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL17090094 | 0.86 | KMT2A (0.38) | KMT2ALMNAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL13565374 | 0.86 | KMT2A (0.38) | KMT2ALMNAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL13565254 | 0.86 | KDM4E (0.36) | KMT2ALMNAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL17090455 | 0.86 | KDM4E (0.36) | KMT2ALMNAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL17090452 | 0.85 | MAPT (0.36) | KMT2ALMNAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL13565537 | 0.85 | MAPT (0.36) | KMT2ALMNAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL17090286 | 0.84 | KDM4E (0.38) | KMT2ALMNAKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8299265-B2 | Amine derivatives having NPY Y5 receptor antagonistic activity and the uses thereof | SHIONOGI & CO., LTD. (JP) | 2012-10-30 | — | — | US | disclosed |