Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13565847 | 0.97 | PKM (0.44) | USP2HTTLMNAALDH1A1KDM1A | |
| SCHEMBL13565864 | 0.84 | USP2 (0.43) | USP2HTTLMNAALDH1A1KDM1A | |
| SCHEMBL10115167 | 0.84 | ALDH1A1 (0.43) | USP2LMNAALDH1A1PKMSMN1; SMN2 | |
| SCHEMBL13565486 | 0.83 | MAPT (0.44) | HTTLMNAALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL13564869 | 0.82 | MAPT (0.43) | HTTLMNAALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL10115153 | 0.81 | SMN1; SMN2 (0.44) | USP2HTTLMNAALDH1A1PKM | |
| SCHEMBL13566034 | 0.81 | PKM (0.44) | USP2HTTLMNAALDH1A1KDM1A | |
| SCHEMBL11935578 | 0.81 | JAK2 (0.35) | ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL11935685 | 0.80 | KDM1A (0.46) | USP2HTTLMNAALDH1A1KDM1A | |
| SCHEMBL11934919 | 0.80 | MAPT (0.41) | HTTLMNAALDH1A1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |
| US-8299265-B2 | Amine derivatives having NPY Y5 receptor antagonistic activity and the uses thereof | SHIONOGI & CO., LTD. (JP) | 2012-10-30 | — | — | US | disclosed |