Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | F7 | P08709 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11936147 | 0.86 | UTS2R (0.41) | UTS2RSMN1; SMN2LMNAHTTF2 | |
| SCHEMBL11936047 | 0.84 | FFAR4 (0.40) | UTS2RSMN1; SMN2ALDH1A1MAPTPOLB | |
| SCHEMBL11935979 | 0.82 | FLT1 (0.41) | UTS2RLMNAMAPTFFAR4CNR2 | |
| SCHEMBL17090248 | 0.82 | KIF11 (0.49) | UTS2RFFAR4CNR2PTGDR2 | |
| SCHEMBL11936059 | 0.81 | UTS2R (0.46) | UTS2RF2F10PRSS1F7 | |
| SCHEMBL10116448 | 0.81 | MAPT (0.48) | SMN1; SMN2LMNAHTTALDH1A1MAPT | |
| SCHEMBL13565908 | 0.80 | SLC22A12 (0.48) | LMNAFFAR4CNR2 | |
| SCHEMBL11935887 | 0.77 | CA1 (0.54) | SMN1; SMN2LMNAHTTALDH1A1MAPT | |
| SCHEMBL11936050 | 0.77 | HDAC3 (0.39) | PPARA | |
| SCHEMBL13565011 | 0.76 | CA1 (0.53) | SMN1; SMN2LMNAHTTALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |
| US-8299265-B2 | Amine derivatives having NPY Y5 receptor antagonistic activity and the uses thereof | SHIONOGI & CO., LTD. (JP) | 2012-10-30 | — | — | US | disclosed |