Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 6/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13565908 | 0.90 | SLC22A12 (0.48) | KIF11CNR2SLC22A12ARCA1 | |
| SCHEMBL11935979 | 0.88 | FLT1 (0.41) | KIF11CNR2ARCA1CA2 | |
| SCHEMBL13565221 | 0.87 | MAPT (0.45) | SLC22A12CA1CA2PTPN11 | |
| SCHEMBL11936047 | 0.86 | FFAR4 (0.40) | KIF11CNR2ARCA1CA2 | |
| SCHEMBL13566041 | 0.86 | CA1 (0.39) | KIF11CNR2SLC22A12CA1CA2 | |
| SCHEMBL13565875 | 0.85 | MAPT (0.42) | CA1CA2PTPN11 | |
| SCHEMBL17090293 | 0.84 | KIF11 (0.48) | KIF11CNR2SLC22A12ARP2RX7 | |
| SCHEMBL13565871 | 0.82 | UTS2R (0.42) | CNR2PTGDR2UTS2RFFAR4 | |
| SCHEMBL13565680 | 0.81 | CA1 (0.45) | CA1CA2 | |
| SCHEMBL13565011 | 0.81 | CA1 (0.53) | CA1CA2PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |