Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | KIF11 | P52732 | 4/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11936113 | 0.90 | PPARA (0.56) | PPARAFFAR1KIF11CA1CA2 | |
| SCHEMBL13565306 | 0.87 | CA1 (0.62) | CA1CA2 | |
| SCHEMBL13565690 | 0.86 | PPARA (0.46) | PPARAFFAR1ALDH1A1 | |
| SCHEMBL13565986 | 0.85 | CA1 (0.49) | PPARACA1CA2 | |
| SCHEMBL13565070 | 0.85 | PPARA (0.50) | PPARAFFAR1KIF11ADRA2ACA1 | |
| SCHEMBL13565065 | 0.84 | KDM4E (0.44) | FFAR1CA1CA2CA12CA7 | |
| SCHEMBL13565366 | 0.84 | PPARA (0.49) | PPARAKIF11ALDH1A1 | |
| SCHEMBL10116639 | 0.83 | PPARA (0.67) | PPARA | |
| SCHEMBL13565877 | 0.83 | HDAC1 (0.55) | PPARAKIF11CA1CA2CA12 | |
| SCHEMBL13566019 | 0.82 | CA1 (0.50) | FFAR1CA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |
| US-8299265-B2 | Amine derivatives having NPY Y5 receptor antagonistic activity and the uses thereof | SHIONOGI & CO., LTD. (JP) | 2012-10-30 | — | — | US | disclosed |