SCHEMBL1356902

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1356484	0.90	SIGMAR1 (0.68)	SIGMAR1KCNH2KMT2AACHE
	SCHEMBL1355084	0.88	SIGMAR1 (0.70)	SIGMAR1KCNH2KMT2AACHE
	SCHEMBL1356533	0.82	SIGMAR1 (0.53)	SIGMAR1KCNH2ALDH1A1CYP1A2CYP2C19
	SCHEMBL1357402	0.82	SIGMAR1 (0.74)	SIGMAR1ALDH1A1CYP1A2CYP2C19ALOX15
	SCHEMBL1354910	0.81	SIGMAR1 (0.47)	SIGMAR1KCNH2ALDH1A1TSHRHTT
	SCHEMBL1357081	0.81	SIGMAR1 (0.64)	SIGMAR1KCNH2ALDH1A1CYP1A2CYP2C19
	SCHEMBL1354972	0.81	SIGMAR1 (1.00)	SIGMAR1KCNH2ALDH1A1CYP1A2CYP2C19
	SCHEMBL1356504	0.79	SIGMAR1 (0.54)	SIGMAR1ALDH1A1TSHRLMNAKMT2A
	SCHEMBL4656770	0.78	SIGMAR1 (0.47)	SIGMAR1KCNH2ALDH1A1LMNAKMT2A
	Oxalic Acid SCHEMBL1355903	0.78	SIGMAR1 (0.67)	SIGMAR1ALDH1A1TSHRHTTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.