Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | NAMPT | P43490 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13569939 | 0.93 | MAPT (0.46) | USP2HDAC1HDAC3HDAC2NAMPT | |
| SCHEMBL4220744 | 0.92 | USP2 (0.53) | USP2HDAC1HDAC3HDAC2NAMPT | |
| SCHEMBL13585752 | 0.92 | USP2 (0.47) | USP2HDAC1NAMPTALDH1A1KMT2A | |
| SCHEMBL13569966 | 0.91 | USP2 (0.46) | USP2HDAC1HDAC3HDAC2NAMPT | |
| SCHEMBL13569951 | 0.91 | USP2 (0.46) | USP2HDAC1HDAC3HDAC2NAMPT | |
| SCHEMBL13569965 | 0.91 | LMNA (0.48) | USP2HDAC1HDAC3HDAC2ALDH1A1 | |
| SCHEMBL13569888 | 0.91 | LMNA (0.44) | USP2HDAC1HDAC3HDAC2ALDH1A1 | |
| SCHEMBL13585902 | 0.91 | KMT2A (0.52) | USP2HDAC1HDAC3HDAC2NAMPT | |
| SCHEMBL13569368 | 0.91 | USP2 (0.43) | USP2HDAC1HDAC3HDAC2NAMPT | |
| SCHEMBL13569733 | 0.90 | LMNA (0.48) | USP2HDAC1HDAC3HDAC2NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2135620-A1 | OCULAR HYPOTENSIVE AGENT COMPRISING COMPOUND CAPABLE OF INHIBITING HISTONE DEACETYLASE AS ACTIVE INGREDIENT | Santen Pharmaceutical Co., Ltd (JP) | 2009-12-23 | — | — | EP | disclosed |
| EP-2133339-A1 | NOVEL (2-AMINOPHENYL)PYRIDINECARBOXAMIDE DERIVATIVE HAVING UREA STRUCTURE | Santen Pharmaceutical Co., Ltd (JP) | 2009-12-16 | — | — | EP | disclosed |