Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4224136 | 0.93 | USP2 (0.52) | LMNAHDAC1HDAC3HDAC2USP2 | |
| SCHEMBL13585619 | 0.92 | KMT2A (0.49) | LMNAHDAC1HDAC3HDAC2USP2 | |
| SCHEMBL13569890 | 0.92 | LMNA (0.49) | LMNAHDAC1HDAC3HDAC2USP2 | |
| SCHEMBL13569951 | 0.92 | USP2 (0.46) | LMNAHDAC1HDAC3HDAC2USP2 | |
| SCHEMBL13569958 | 0.92 | LMNA (0.49) | LMNAHDAC1HDAC3HDAC2USP2 | |
| SCHEMBL13569894 | 0.92 | KMT2A (0.49) | LMNAHDAC1HDAC3HDAC2USP2 | |
| SCHEMBL13569966 | 0.91 | USP2 (0.46) | LMNAHDAC1HDAC3HDAC2USP2 | |
| SCHEMBL13569366 | 0.90 | USP2 (0.45) | HDAC1HDAC3HDAC2USP2ALDH1A1 | |
| SCHEMBL13570025 | 0.90 | HDAC1 (0.47) | LMNAHDAC1HDAC3HDAC2ALDH1A1 | |
| SCHEMBL13585741 | 0.90 | ALDH1A1 (0.49) | LMNAHDAC1HDAC3HDAC2USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2133339-A1 | NOVEL (2-AMINOPHENYL)PYRIDINECARBOXAMIDE DERIVATIVE HAVING UREA STRUCTURE | Santen Pharmaceutical Co., Ltd (JP) | 2009-12-16 | — | — | EP | disclosed |